Simple, rapid method for detecting phase transitions of lipids

L. Erdei, I. Csorba, H. X. Thuyen

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A simple rapid method was worked out for studying the physical and structural state of lipids by measuring the refractive indices of a layered lipid film. Melting processes of n-paraffins and phase transitions of phospholipids and the lecithin-cholesterol system also can be followed as a function of temperature. In accordance with data from the relevant literature, the measured refractive indices show that cholesterol lowers the phase transition temperature of lecithin. By isorefraction curves, the most ordered structure of the layers is indicated to occur at the equimolar ratio of cholesterol and lecithin. The method may be applied to study the effect of lipid-soluble agents upon lipid structure and is applicable for routine investigations and industrial purposes as well.

Original languageEnglish
Pages (from-to)115-117
Number of pages3
JournalLipids
Volume10
Issue number2
DOIs
Publication statusPublished - Feb 1975

Fingerprint

Phase Transition
phase transition
rapid methods
Lecithins
Phase transitions
phosphatidylcholines
Lipids
Refractometry
refractive index
Cholesterol
cholesterol
lipids
Refractive index
Transition Temperature
melting
Paraffin
alkanes
Freezing
Phospholipids
phospholipids

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Food Science
  • Organic Chemistry
  • Cell Biology

Cite this

Simple, rapid method for detecting phase transitions of lipids. / Erdei, L.; Csorba, I.; Thuyen, H. X.

In: Lipids, Vol. 10, No. 2, 02.1975, p. 115-117.

Research output: Contribution to journalArticle

Erdei, L. ; Csorba, I. ; Thuyen, H. X. / Simple, rapid method for detecting phase transitions of lipids. In: Lipids. 1975 ; Vol. 10, No. 2. pp. 115-117.
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