Simple partial seizures (isolated auras) in medial temporal lobe epilepsy

J. Janszky, R. Schulz, A. Ebner

Research output: Contribution to journalArticle

13 Citations (Scopus)


We analysed whether the medial temporal lobe epilepsy (MTLE) with isolated auras makes any difference in the clinical picture in comparison with MTLE in which only complex partial seizures (CPS) occur. We included 100 patients (aged 16-59 years) with unilateral medial temporal lobe lesions who consecutively underwent presurgical evaluation due to intractable MTLE and who became completely aura- and seizure-free after the anterior temporal resection. Preoperatively, isolated auras were present in 70 patients. These patients were categorised into the IA group. The remaining 30 patients in whom the auras preceded seizures were categorised into the NIA group. We found no difference between the two groups for the age at onset, epilepsy duration or aura types. Conversely, a right-sided epileptogenic region (61%) occurred more frequently in the IA group than in the NIA group (27%, P = 0.001). Conclusively, isolated auras show affinity to the right hemisphere. One explanation may be that seizures stop more quickly in the right hemisphere. Another hypothesis is that consciousness can be disturbed much easier by the ictal activity in left temporal seizures: auras evolve more frequently to CPS due to the disturbance of consciousness.

Original languageEnglish
Pages (from-to)247-249
Number of pages3
Issue number4
Publication statusPublished - Jun 2004


  • Isolated aura
  • Lateralisation
  • Mesial temporal lobe epilepsy
  • Right hemisphere
  • Simple partial seizures

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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