Simple and Condensed β‐Lactams, XVII. Monobactams Acylated with Isoxazoleacetic and Isoxazolecarboxylic Acids

József Nagy, József Nyitrai, M. Kajtár-Peredy

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3 Citations (Scopus)

Abstract

Analogues of aztreonam (1a) and carumonam (1b) were prepared by acylation of 3‐aminomonobactamic acid derivatives with several new and known isoxazoleacetic and isoxazolecarboxylic acid derivatives 3–10. None of the resulting new monobactams 11–18, 41a, 41b, and 54a exhibited any significant antibacterial activity.

Original languageEnglish
Pages (from-to)815-821
Number of pages7
JournalLiebigs Annalen der Chemie
Volume1993
Issue number8
DOIs
Publication statusPublished - 1993

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Keywords

  • Antibiotics
  • Aztreonam analogues
  • Carumonam analogues
  • β‐Lactams

ASJC Scopus subject areas

  • Medicine(all)

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