Signs of the times: the need for a stereochemically informative generic name system

Miklós Simonyi, Joseph Gal, Bernard Testa

Research output: Contribution to journalComment/debate

33 Citations (Scopus)

Abstract

'Research and clinical pharmacologists frequently present data on impure drugs'. Because generic drug names often hide the fact that different stereoisomers (possibly with different pharmacological properties) may be present in the 'pure' preparation, this statement is all too frequently true. However, the problem may be overcome by pharmacologists and publishers adopting the user-friendly SIGNS nomenclature devised and explained here by Miklos Simonyi, Joseph Gal and Bernard Testa. The acronym stands for 'stereochemically informative generic name system'. Seven prefixes are offered to describe the stereochemical nature of any drug. The appropriate prefix would be attached to the generic name. A generic name without prefix would indicate a single agent with no stereoisomers.

Original languageEnglish
Pages (from-to)349-354
Number of pages6
JournalTrends in Pharmacological Sciences
Volume10
Issue number9
DOIs
Publication statusPublished - Sep 1989

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology

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