Significant differences in capillary electrophoretic patterns of follicular fluids and sera from women pre-treated for in vitro fertilization

Melinda Rezeli, Bernadett Világhy, Ferenc Kilár, Katalin Kanyó, Béla Török, Attila Török

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Human ovarian follicular fluids and sera obtained from women pre-treated for in vitro fertilization (IVF) were investigated by capillary zone electrophoresis. Comparison of the matching physiological liquids showed substantial differences in the electrophoretic patterns. Significant decrease in the α1- and γ-fractions of follicular fluids of every woman were observed, whereas other fractions of the samples did not show such alterations. Since follicular fluid is a product of both, secretion by granulosa cells and diffusion from the theca capillaries, we can assume that the forced production of follicular fluid upon hormone stimulation (with gonadotropin releasing hormone (GnRH), follicle stimulating hormone (FSH) and corionic gonadotroph hormone (hCG)) may play role in the uneven presence of the proteins.

Original languageEnglish
Pages (from-to)151-156
Number of pages6
JournalJournal of biochemical and biophysical methods
Issue number1-3
Publication statusPublished - Oct 1 2002



  • Capillary electrophoresis
  • Follicular fluid
  • In vitro fertilization
  • Serum

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry

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