Transmission electron microscopy has been confirmed as an important supplementary technique to light microscopy and immunohistology in the evaluation of kidney needle biopsies. It contributes diagnostically significant or prognostically important information in about one-fifth of biopsies, especially by demonstrating characteristic changes of the glomerular basement membrane and by enabling the evaluation of the distribution, quantity, and ultrastructure of various immune and nonimmune extracellular protein deposits. Electron microscopy has made a significant scientific contribution in recent studies of fibrillary glomerulopathies, hantavirus nephropathy, and Balkan endemic nephropathy.
|Number of pages||4|
|Journal||Journal of Computer-Assisted Microscopy|
|Publication status||Published - Dec 1 1996|
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials