Signet-ring cell carcinoma arising from the urinary bladder.

I. Romics, Eszter Székely, Attila Szendroi

Research output: Contribution to journalArticle

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Abstract

INTRODUCTION: Signet-ring cell carcinoma of the urinary bladder can be primary - arising from the bladder wall or urachus remnants - or metastatic from tumors originating in the stomach, colon, or breast. Saphir first described primary signet-ring cell cancer of the urinary bladder in 1955. Less than 100 cases have been reported in the literature since then. CASE REPORT: We report a case of a 45-year-old woman who was admitted with gross hematuria. Cystoscopy revealed a necrotic tumor on the left bladder wall. A transurethral biopsy showed signet-ring cell carcinoma. The bladder tumor was diagnosed as the primary one. Radical cystectomy was performed with ureterosigmoidostomy (Mainz pouch II). Histological examination showed a primary signet-ring cell carcinoma of the bladder (pT3bN0M0). Following surgery, the patient received adjuvant chemotherapy with cisplatin and fluorouracil. CONCLUSIONS: Primary signet-ring cell carcinoma of the urinary bladder is an extremely rare tumor, accounting for approximately 0.24% of all bladder malignances. Patients with this type of cancer generally have a poor prognosis. However, our patient is free of disease 5 years after radical cystectomy.

Original languageEnglish
Pages (from-to)4266-4268
Number of pages3
JournalCanadian Journal of Urology
Volume15
Issue number5
Publication statusPublished - Oct 2008

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Signet Ring Cell Carcinoma
Urinary Bladder
Cystectomy
Urinary Bladder Neoplasms
Neoplasms
Urachus
Cystoscopy
Hematuria
Adjuvant Chemotherapy
Fluorouracil
Cisplatin
Stomach
Colon
Breast
Biopsy

ASJC Scopus subject areas

  • Medicine(all)

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Signet-ring cell carcinoma arising from the urinary bladder. / Romics, I.; Székely, Eszter; Szendroi, Attila.

In: Canadian Journal of Urology, Vol. 15, No. 5, 10.2008, p. 4266-4268.

Research output: Contribution to journalArticle

Romics, I, Székely, E & Szendroi, A 2008, 'Signet-ring cell carcinoma arising from the urinary bladder.', Canadian Journal of Urology, vol. 15, no. 5, pp. 4266-4268.
Romics, I. ; Székely, Eszter ; Szendroi, Attila. / Signet-ring cell carcinoma arising from the urinary bladder. In: Canadian Journal of Urology. 2008 ; Vol. 15, No. 5. pp. 4266-4268.
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