Signaling pathways leading to apoptosis or survival in immature and mature B cells

G. Sármay, G. Koncz, Cs Bodor, D. Kövesdi, R. Gáti, J. Gergely

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In the absence of phosphorylated Gab2, immature B cells are unable to maintain a prolonged signal transduction, which is necessary for the transcriptional regulation and activation of the cells. Thus, the lack of Gab2 phosphorylation may drive immature B cells to apoptosis.

Original languageEnglish
Pages (from-to)181-185
Number of pages5
JournalAnnals of the New York Academy of Sciences
Volume973
Publication statusPublished - 2002

Fingerprint

B-Lymphoid Precursor Cells
Cells
Apoptosis
Signal transduction
Phosphorylation
Transcriptional Activation
Signal Transduction
Chemical activation
Pathway

Keywords

  • Apoptosis
  • B cell
  • Development
  • Signaling

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Signaling pathways leading to apoptosis or survival in immature and mature B cells. / Sármay, G.; Koncz, G.; Bodor, Cs; Kövesdi, D.; Gáti, R.; Gergely, J.

In: Annals of the New York Academy of Sciences, Vol. 973, 2002, p. 181-185.

Research output: Contribution to journalArticle

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AU - Gergely, J.

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