Sex differences in prostaglandin metabolism

Á Gecse, Anna Ottlecz, Ilona Schäffer, Anna Bujdosć, G. Telegdy

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Prostaglandin E2 (PGE2), PGF2alfa and PGD2 were synthetized from [1-14C]-arachidonic acid by rat kidney medulla microsomal fraction. The formation of each prostaglandin was significantly less in female animals than in males. The rate of inactivation of [3H]-PGF2alfa by kidney cortex cytosol was almost linear with the time of incubation during the first 30 min. The production of PGF2alfa metabolite (13,14-dihydro-15-keto PGF2alfa) was higher in male rats than in females.

Original languageEnglish
Pages (from-to)643-647
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume86
Issue number3
DOIs
Publication statusPublished - Feb 14 1979

Fingerprint

Dinoprost
Metabolism
Sex Characteristics
Prostaglandins
Rats
Kidney Medulla
Prostaglandin D2
Kidney Cortex
Metabolites
Dinoprostone
Arachidonic Acid
Cytosol
Animals

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Sex differences in prostaglandin metabolism. / Gecse, Á; Ottlecz, Anna; Schäffer, Ilona; Bujdosć, Anna; Telegdy, G.

In: Biochemical and Biophysical Research Communications, Vol. 86, No. 3, 14.02.1979, p. 643-647.

Research output: Contribution to journalArticle

Gecse, Á ; Ottlecz, Anna ; Schäffer, Ilona ; Bujdosć, Anna ; Telegdy, G. / Sex differences in prostaglandin metabolism. In: Biochemical and Biophysical Research Communications. 1979 ; Vol. 86, No. 3. pp. 643-647.
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