Severe acrocyanosis precipitated by cold agglutinin secondary to infection with Mycoplasma pneumoniae in a pediatric patient

Bernadett Mosdósi, Zoltán Nyul, Arnold Nagy, K. Bölcskei, T. Decsi, Z. Helyes

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This is the first report describing a severe form of cold agglutinin- induced acrocyanosis with cutaneous necrosis after Mycoplasma infection in a 9-year-old patient without any other severe symptoms and laboratory alterations. We also present the results of two non-invasive methods used to determine the viability of tissues, degree of tissue perfusion impairment, and the responsiveness of the microvasculature. Laser Doppler flowmetry and laser speckle contrast imaging, both suitable to measure tissue blood perfusion non-invasively, have been used in the diagnosis and follow-up of various peripheral vascular diseases. In our patient, we demonstrated remarkably reduced microcirculation before the treatment and a significant perfusion increase in the acral regions after pentoxifylline therapy. The investigational techniques were useful tools to assess and quantify the severity of peripheral perfusion disturbances and to monitor the efficacy of the treatment in our patient.

Original languageEnglish
Pages (from-to)424-430
Number of pages7
JournalCroatian Medical Journal
Volume58
Issue number6
DOIs
Publication statusPublished - Dec 1 2017

Fingerprint

Mycoplasma pneumoniae
Coinfection
Perfusion
Pediatrics
Mycoplasma Infections
Tissue Survival
Pentoxifylline
Laser-Doppler Flowmetry
Peripheral Vascular Diseases
Microcirculation
Microvessels
Lasers
Necrosis
Extremities
Skin
cold agglutinins
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Severe acrocyanosis precipitated by cold agglutinin secondary to infection with Mycoplasma pneumoniae in a pediatric patient. / Mosdósi, Bernadett; Nyul, Zoltán; Nagy, Arnold; Bölcskei, K.; Decsi, T.; Helyes, Z.

In: Croatian Medical Journal, Vol. 58, No. 6, 01.12.2017, p. 424-430.

Research output: Contribution to journalArticle

@article{01359ceb8b254933b12c19e0d27c1a1d,
title = "Severe acrocyanosis precipitated by cold agglutinin secondary to infection with Mycoplasma pneumoniae in a pediatric patient",
abstract = "This is the first report describing a severe form of cold agglutinin- induced acrocyanosis with cutaneous necrosis after Mycoplasma infection in a 9-year-old patient without any other severe symptoms and laboratory alterations. We also present the results of two non-invasive methods used to determine the viability of tissues, degree of tissue perfusion impairment, and the responsiveness of the microvasculature. Laser Doppler flowmetry and laser speckle contrast imaging, both suitable to measure tissue blood perfusion non-invasively, have been used in the diagnosis and follow-up of various peripheral vascular diseases. In our patient, we demonstrated remarkably reduced microcirculation before the treatment and a significant perfusion increase in the acral regions after pentoxifylline therapy. The investigational techniques were useful tools to assess and quantify the severity of peripheral perfusion disturbances and to monitor the efficacy of the treatment in our patient.",
author = "Bernadett Mosd{\'o}si and Zolt{\'a}n Nyul and Arnold Nagy and K. B{\"o}lcskei and T. Decsi and Z. Helyes",
year = "2017",
month = "12",
day = "1",
doi = "10.3325/cmj.2017.58.424",
language = "English",
volume = "58",
pages = "424--430",
journal = "Croatian Medical Journal",
issn = "0353-9504",
publisher = "Medicinska Naklada d.o.o",
number = "6",

}

TY - JOUR

T1 - Severe acrocyanosis precipitated by cold agglutinin secondary to infection with Mycoplasma pneumoniae in a pediatric patient

AU - Mosdósi, Bernadett

AU - Nyul, Zoltán

AU - Nagy, Arnold

AU - Bölcskei, K.

AU - Decsi, T.

AU - Helyes, Z.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - This is the first report describing a severe form of cold agglutinin- induced acrocyanosis with cutaneous necrosis after Mycoplasma infection in a 9-year-old patient without any other severe symptoms and laboratory alterations. We also present the results of two non-invasive methods used to determine the viability of tissues, degree of tissue perfusion impairment, and the responsiveness of the microvasculature. Laser Doppler flowmetry and laser speckle contrast imaging, both suitable to measure tissue blood perfusion non-invasively, have been used in the diagnosis and follow-up of various peripheral vascular diseases. In our patient, we demonstrated remarkably reduced microcirculation before the treatment and a significant perfusion increase in the acral regions after pentoxifylline therapy. The investigational techniques were useful tools to assess and quantify the severity of peripheral perfusion disturbances and to monitor the efficacy of the treatment in our patient.

AB - This is the first report describing a severe form of cold agglutinin- induced acrocyanosis with cutaneous necrosis after Mycoplasma infection in a 9-year-old patient without any other severe symptoms and laboratory alterations. We also present the results of two non-invasive methods used to determine the viability of tissues, degree of tissue perfusion impairment, and the responsiveness of the microvasculature. Laser Doppler flowmetry and laser speckle contrast imaging, both suitable to measure tissue blood perfusion non-invasively, have been used in the diagnosis and follow-up of various peripheral vascular diseases. In our patient, we demonstrated remarkably reduced microcirculation before the treatment and a significant perfusion increase in the acral regions after pentoxifylline therapy. The investigational techniques were useful tools to assess and quantify the severity of peripheral perfusion disturbances and to monitor the efficacy of the treatment in our patient.

UR - http://www.scopus.com/inward/record.url?scp=85040469297&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85040469297&partnerID=8YFLogxK

U2 - 10.3325/cmj.2017.58.424

DO - 10.3325/cmj.2017.58.424

M3 - Article

VL - 58

SP - 424

EP - 430

JO - Croatian Medical Journal

JF - Croatian Medical Journal

SN - 0353-9504

IS - 6

ER -