A polycystás ovarium szindróma gyógyszeres kezelésének bizonyos kérdései

Translated title of the contribution: Several questions of medical treatment of polycystic ovary syndrome

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Polycystic ovary syndrome is an endemic disease, thus its treatment is of great importance. In polycystic ovary syndrome, metformin decreases androgen levels, improves menstrual irregularity, hirsutism, ovulation ratio, and the efficiency of lifestyle interventions on visceral obesity, endothelial function and LDL-cholesterol level. It seems plausible to suppose that metformin decreases the incidence of diabetes in this group of patients. Metformin is superior to oral contraceptives/antiandrogens in respect of its effect on triglyceride level and insulin sensitivity, however, it is less effective in decreasing androgen levels, normalisation of the menstrual cycle and supposedly in the prevention of endometrial cancer. Metformin therapy improves fertility, however, when infertility is the main problem, it is not indicated as the primary treatment. In this case, ovulation induction, ovary drilling, as well as in vitro fertilization are warranted that can be supported by metformin therapy is some cases.

Original languageHungarian
Pages (from-to)189-193
Number of pages5
JournalLege Artis Medicinae
Volume20
Issue number3-4
Publication statusPublished - Apr 2010

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Polycystic Ovary Syndrome
Metformin
Androgens
Therapeutics
Androgen Antagonists
Endemic Diseases
Hirsutism
Abdominal Obesity
Ovulation Induction
Fertilization in Vitro
Endometrial Neoplasms
Menstrual Cycle
Oral Contraceptives
Ovulation
LDL Cholesterol
Infertility
Fertility
Insulin Resistance
Life Style
Ovary

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A polycystás ovarium szindróma gyógyszeres kezelésének bizonyos kérdései. / Bajnok, L.

In: Lege Artis Medicinae, Vol. 20, No. 3-4, 04.2010, p. 189-193.

Research output: Contribution to journalArticle

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