Serum Ghrelin Level and TNF-α/Ghrelin Ratio in Patients with Previous Myocardial Infarction

Krisztián Vörös, Z. Prohászka, Edit Kaszás, Anna Alliquander, András Terebesy, Ferenc Horváth, Leonard Janik, Ágnes Sima, Judit Forrai, K. Cseh, L. Kalabay

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background and Aims: Studies investigating serum ghrelin level in atherosclerosis yielded contradictory results. Interaction of ghrelin with adipocytokines is obscure in cardiovascular diseases. We undertook this study to determine which molecules influence ghrelin level and to see whether post-myocardial infarction (MI) patients have decreased ghrelin levels. Methods: In this cross-sectional study, acyl-ghrelin concentration was determined by radioimmunoassay in sera of 171 patients (ages 62 ± 6 years, mean ± SD) with previous MI and 81 age-matched referent subjects. We evaluated the associations of ghrelin with insulin, adiponectin, leptin, resistin, fetuin-A and tumor necrosis factor-alpha (TNF-α). Results: Patients had lower ghrelin levels compared to referent subjects (240.55 ± 59.33 vs. 337.96 ± 30.75 pg/mL, p 2 = 0.199, p 2 (1) = 215.6, p

Original languageEnglish
Pages (from-to)548-554
Number of pages7
JournalArchives of Medical Research
Volume43
Issue number7
DOIs
Publication statusPublished - Oct 2012

Fingerprint

Ghrelin
Tumor Necrosis Factor-alpha
Myocardial Infarction
Serum
alpha-2-HS-Glycoprotein
Resistin
Adipokines
Adiponectin
Leptin
Radioimmunoassay
Atherosclerosis
Cardiovascular Diseases
Cross-Sectional Studies
Insulin

Keywords

  • Adiponectin
  • Ghrelin
  • Insulin
  • Myocardial infarction
  • Tumor necrosis factor-α

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Serum Ghrelin Level and TNF-α/Ghrelin Ratio in Patients with Previous Myocardial Infarction. / Vörös, Krisztián; Prohászka, Z.; Kaszás, Edit; Alliquander, Anna; Terebesy, András; Horváth, Ferenc; Janik, Leonard; Sima, Ágnes; Forrai, Judit; Cseh, K.; Kalabay, L.

In: Archives of Medical Research, Vol. 43, No. 7, 10.2012, p. 548-554.

Research output: Contribution to journalArticle

Vörös, K, Prohászka, Z, Kaszás, E, Alliquander, A, Terebesy, A, Horváth, F, Janik, L, Sima, Á, Forrai, J, Cseh, K & Kalabay, L 2012, 'Serum Ghrelin Level and TNF-α/Ghrelin Ratio in Patients with Previous Myocardial Infarction', Archives of Medical Research, vol. 43, no. 7, pp. 548-554. https://doi.org/10.1016/j.arcmed.2012.09.002
Vörös, Krisztián ; Prohászka, Z. ; Kaszás, Edit ; Alliquander, Anna ; Terebesy, András ; Horváth, Ferenc ; Janik, Leonard ; Sima, Ágnes ; Forrai, Judit ; Cseh, K. ; Kalabay, L. / Serum Ghrelin Level and TNF-α/Ghrelin Ratio in Patients with Previous Myocardial Infarction. In: Archives of Medical Research. 2012 ; Vol. 43, No. 7. pp. 548-554.
@article{d94e4bf14d6f4ea6bc3b3c0d177648d9,
title = "Serum Ghrelin Level and TNF-α/Ghrelin Ratio in Patients with Previous Myocardial Infarction",
abstract = "Background and Aims: Studies investigating serum ghrelin level in atherosclerosis yielded contradictory results. Interaction of ghrelin with adipocytokines is obscure in cardiovascular diseases. We undertook this study to determine which molecules influence ghrelin level and to see whether post-myocardial infarction (MI) patients have decreased ghrelin levels. Methods: In this cross-sectional study, acyl-ghrelin concentration was determined by radioimmunoassay in sera of 171 patients (ages 62 ± 6 years, mean ± SD) with previous MI and 81 age-matched referent subjects. We evaluated the associations of ghrelin with insulin, adiponectin, leptin, resistin, fetuin-A and tumor necrosis factor-alpha (TNF-α). Results: Patients had lower ghrelin levels compared to referent subjects (240.55 ± 59.33 vs. 337.96 ± 30.75 pg/mL, p 2 = 0.199, p 2 (1) = 215.6, p",
keywords = "Adiponectin, Ghrelin, Insulin, Myocardial infarction, Tumor necrosis factor-α",
author = "Kriszti{\'a}n V{\"o}r{\"o}s and Z. Proh{\'a}szka and Edit Kasz{\'a}s and Anna Alliquander and Andr{\'a}s Terebesy and Ferenc Horv{\'a}th and Leonard Janik and {\'A}gnes Sima and Judit Forrai and K. Cseh and L. Kalabay",
year = "2012",
month = "10",
doi = "10.1016/j.arcmed.2012.09.002",
language = "English",
volume = "43",
pages = "548--554",
journal = "Archives of Medical Research",
issn = "0188-4409",
publisher = "Elsevier Inc.",
number = "7",

}

TY - JOUR

T1 - Serum Ghrelin Level and TNF-α/Ghrelin Ratio in Patients with Previous Myocardial Infarction

AU - Vörös, Krisztián

AU - Prohászka, Z.

AU - Kaszás, Edit

AU - Alliquander, Anna

AU - Terebesy, András

AU - Horváth, Ferenc

AU - Janik, Leonard

AU - Sima, Ágnes

AU - Forrai, Judit

AU - Cseh, K.

AU - Kalabay, L.

PY - 2012/10

Y1 - 2012/10

N2 - Background and Aims: Studies investigating serum ghrelin level in atherosclerosis yielded contradictory results. Interaction of ghrelin with adipocytokines is obscure in cardiovascular diseases. We undertook this study to determine which molecules influence ghrelin level and to see whether post-myocardial infarction (MI) patients have decreased ghrelin levels. Methods: In this cross-sectional study, acyl-ghrelin concentration was determined by radioimmunoassay in sera of 171 patients (ages 62 ± 6 years, mean ± SD) with previous MI and 81 age-matched referent subjects. We evaluated the associations of ghrelin with insulin, adiponectin, leptin, resistin, fetuin-A and tumor necrosis factor-alpha (TNF-α). Results: Patients had lower ghrelin levels compared to referent subjects (240.55 ± 59.33 vs. 337.96 ± 30.75 pg/mL, p 2 = 0.199, p 2 (1) = 215.6, p

AB - Background and Aims: Studies investigating serum ghrelin level in atherosclerosis yielded contradictory results. Interaction of ghrelin with adipocytokines is obscure in cardiovascular diseases. We undertook this study to determine which molecules influence ghrelin level and to see whether post-myocardial infarction (MI) patients have decreased ghrelin levels. Methods: In this cross-sectional study, acyl-ghrelin concentration was determined by radioimmunoassay in sera of 171 patients (ages 62 ± 6 years, mean ± SD) with previous MI and 81 age-matched referent subjects. We evaluated the associations of ghrelin with insulin, adiponectin, leptin, resistin, fetuin-A and tumor necrosis factor-alpha (TNF-α). Results: Patients had lower ghrelin levels compared to referent subjects (240.55 ± 59.33 vs. 337.96 ± 30.75 pg/mL, p 2 = 0.199, p 2 (1) = 215.6, p

KW - Adiponectin

KW - Ghrelin

KW - Insulin

KW - Myocardial infarction

KW - Tumor necrosis factor-α

UR - http://www.scopus.com/inward/record.url?scp=84869820009&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84869820009&partnerID=8YFLogxK

U2 - 10.1016/j.arcmed.2012.09.002

DO - 10.1016/j.arcmed.2012.09.002

M3 - Article

VL - 43

SP - 548

EP - 554

JO - Archives of Medical Research

JF - Archives of Medical Research

SN - 0188-4409

IS - 7

ER -