Serum antibodies to HTLV-I in human demyelinating disease

L. Epstein, B. Blumberg, J. Crowley, S. Komoly, J. Goudsmit, S. Cook, P. Dowling

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Serum HTLV-I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV-I core protein antigens and an immunoblot assay with E. coli-expressed P21E transmembrane protein was employed to detect antibodies to HTLV-I envelope antigens. No serologic evidence of prior HTLV-I infection in our population of multiple sclerosis (MS) or Guillain-Barre Syndrome (GBS) patients was found.

Original languageEnglish
Pages (from-to)231-233
Number of pages3
JournalActa Neurologica Scandinavica
Volume75
Issue number4
Publication statusPublished - 1987

Fingerprint

HTLV-I Antibodies
Demyelinating Diseases
Multiple Sclerosis
HTLV-I Antigens
HTLV-I Infections
Agglutination Tests
Human T-lymphotropic virus 1
Guillain-Barre Syndrome
Serum
Proteins
Research Design
Escherichia coli
Antigens
Control Groups
Antibodies
Population

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Epstein, L., Blumberg, B., Crowley, J., Komoly, S., Goudsmit, J., Cook, S., & Dowling, P. (1987). Serum antibodies to HTLV-I in human demyelinating disease. Acta Neurologica Scandinavica, 75(4), 231-233.

Serum antibodies to HTLV-I in human demyelinating disease. / Epstein, L.; Blumberg, B.; Crowley, J.; Komoly, S.; Goudsmit, J.; Cook, S.; Dowling, P.

In: Acta Neurologica Scandinavica, Vol. 75, No. 4, 1987, p. 231-233.

Research output: Contribution to journalArticle

Epstein, L, Blumberg, B, Crowley, J, Komoly, S, Goudsmit, J, Cook, S & Dowling, P 1987, 'Serum antibodies to HTLV-I in human demyelinating disease', Acta Neurologica Scandinavica, vol. 75, no. 4, pp. 231-233.
Epstein L, Blumberg B, Crowley J, Komoly S, Goudsmit J, Cook S et al. Serum antibodies to HTLV-I in human demyelinating disease. Acta Neurologica Scandinavica. 1987;75(4):231-233.
Epstein, L. ; Blumberg, B. ; Crowley, J. ; Komoly, S. ; Goudsmit, J. ; Cook, S. ; Dowling, P. / Serum antibodies to HTLV-I in human demyelinating disease. In: Acta Neurologica Scandinavica. 1987 ; Vol. 75, No. 4. pp. 231-233.
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