Serotoninergic endings on VIP-neurons in the suprachiasmatic nucleus and on ACTH-neurons in the arcuate nucleus of the rat hypothalamus. A combination of high resolution autoradiography and electron microscopic immunocytochemistry

J. Kiss, Cs Léránth, B. Halász

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

A combination of immunocytochemistry with transmitter specific autoradiography at the electron microscopic level was used to identify vasoactive intestinal polypeptide (VIP)- or ACTH-containing neurons and serotoninergic nerve terminals in the suprachiasmatic (SCN) and arcuate nuclei (AN). We observed nerve terminals showing selective uptake of [3H]serotonin forming synaptic contact with perikarya or dendrites where the postsynaptic structures exhibited VIP-like immunoreactivity in the SCN and ACTH-like immunoreactivity in the AN. The findings provide ultrastructural evidence that serotoninergic nerve fibers terminate on VIP-neurons in the SCN and on ACTH-neurons in the AN.

Original languageEnglish
Pages (from-to)119-124
Number of pages6
JournalNeuroscience Letters
Volume44
Issue number2
DOIs
Publication statusPublished - Feb 10 1984

Keywords

  • adrenocorticotrophic hormone neurons
  • arcuate nucleus
  • autoradiography
  • hypothalamus
  • immunocytochemistry combination
  • peptides
  • serotoninergic endings
  • suprachiasmatic nucleus
  • vasoactive intestinal polypeptide neurons

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Serotoninergic endings on VIP-neurons in the suprachiasmatic nucleus and on ACTH-neurons in the arcuate nucleus of the rat hypothalamus. A combination of high resolution autoradiography and electron microscopic immunocytochemistry'. Together they form a unique fingerprint.

  • Cite this