Seromuscular gastrocystoplasty in dogs

Attila M. Vastyan, Andrew B. Pinter, Andrew P. Farkas, Peter Vajda, J. Lantos, G. Méhes, E. Rőth

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Introduction: The aim of this study was to investigate the feasibility of seromuscular gastrocystoplasty (SGCP) in an animal model and to compare it to conventional gastrocystoplasty (CGCP). Materials and Methods: CGCP and SGCP (using gastric segments without mucosa) were each performed in 6 dogs. In both procedures, two-thirds of the dome of the bladder were excised and the gastric segment anastomosed to the bladder remnant. Cystography, cystomanometry, measurements of urine pH, and gross and microscopic pathological studies were carried out preoperatively, and postoperatively, at 6 and 12 weeks. Results: All seromuscular gastric segments proved viable, and 6 weeks after the operation they were covered by a thin layer of transitional epithelium, which had gradually thickened by the end of the 12-week follow-up. There was no difference in bladder capacity and compliance between the two groups, however, fasting urinary pH values were higher (less acidic) in the SGCP group. Conclusions: Stripping off the mucosa of the gastric segment appears to stop hydrochloric acid secretion, thereby lessening the possible risk of ulceration, perforation, dysuria-haematuria, metaplasia and malignancy. The uroepithelium overgrowth of the seromuscular gastric segments might provide a more physiological neo-bladder than when using full-thickness gastrocystoplasty.

Original languageEnglish
Pages (from-to)215-218
Number of pages4
JournalUrologia Internationalis
Volume71
Issue number2
DOIs
Publication statusPublished - 2003

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Stomach
Urinary Bladder
Dogs
Dysuria
Hydrochloric Acid
Metaplasia
Hematuria
Gastric Mucosa
Compliance
Fasting
Mucous Membrane
Epithelium
Animal Models
Urine
Neoplasms

Keywords

  • Bladder augmentation
  • Gastrocystoplasty
  • Seromuscular gastrocystoplasty

ASJC Scopus subject areas

  • Urology

Cite this

Seromuscular gastrocystoplasty in dogs. / Vastyan, Attila M.; Pinter, Andrew B.; Farkas, Andrew P.; Vajda, Peter; Lantos, J.; Méhes, G.; Rőth, E.

In: Urologia Internationalis, Vol. 71, No. 2, 2003, p. 215-218.

Research output: Contribution to journalArticle

Vastyan, AM, Pinter, AB, Farkas, AP, Vajda, P, Lantos, J, Méhes, G & Rőth, E 2003, 'Seromuscular gastrocystoplasty in dogs', Urologia Internationalis, vol. 71, no. 2, pp. 215-218. https://doi.org/10.1159/000071851
Vastyan, Attila M. ; Pinter, Andrew B. ; Farkas, Andrew P. ; Vajda, Peter ; Lantos, J. ; Méhes, G. ; Rőth, E. / Seromuscular gastrocystoplasty in dogs. In: Urologia Internationalis. 2003 ; Vol. 71, No. 2. pp. 215-218.
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