Serologic evidence of Crimean-Congo hemorrhagic fever virus infection in Hungary

Viktória Németh, Miklós Oldal, L. Egyed, Miklós Gyuranecz, K. Erdélyi, K. Kvell, Nikolay Kalvatchev, Herve Zeller, K. Bányai, F. Jakab

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Crimean-Congo hemorrhagic fever virus (CCHFV) is a typical tick-borne pathogen that causes an increasing number of severe infections in many parts of Africa, Asia, the Middle East, and the Balkans, as well as in some other parts of Europe. The virus is transmitted primarily by Hyalomma spp., and the spectrum of natural hosts for CCHFV is broad, including wild and domestic animals. Although, the presence of CCHFV was hypothesized in Hungary, no significant research activity has been carried out in the past 30 years. In the present study, we provide serological evidence of CCHFV infection in Lepus europeus using newly developed antibody detection assays. Of 198 samples, 12 (6%) were positive for immunoglobulin G antibody against CCHFV, with 2 independent detection assays. This observation indicates a need for a large-scale surveillance to estimate the potential public health risk of CCHFV in Hungary.

Original languageEnglish
Pages (from-to)270-272
Number of pages3
JournalVector-Borne and Zoonotic Diseases
Volume13
Issue number4
DOIs
Publication statusPublished - Apr 1 2013

Fingerprint

Crimean-Congo hemorrhagic fever virus
Hungary
Virus Diseases
Balkan Peninsula
Hares
Wild Animals
Middle East
Antibodies
Domestic Animals
Ticks
Public Health
Immunoglobulin G
Viruses
Infection
Research

Keywords

  • Crimean-Congo hemorrhagic fever virus
  • Enzymelinkedimmunosorbent assay
  • European brown hare
  • Hungary.
  • Transgenic cell line

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology
  • Virology
  • Medicine(all)

Cite this

Serologic evidence of Crimean-Congo hemorrhagic fever virus infection in Hungary. / Németh, Viktória; Oldal, Miklós; Egyed, L.; Gyuranecz, Miklós; Erdélyi, K.; Kvell, K.; Kalvatchev, Nikolay; Zeller, Herve; Bányai, K.; Jakab, F.

In: Vector-Borne and Zoonotic Diseases, Vol. 13, No. 4, 01.04.2013, p. 270-272.

Research output: Contribution to journalArticle

Németh, Viktória ; Oldal, Miklós ; Egyed, L. ; Gyuranecz, Miklós ; Erdélyi, K. ; Kvell, K. ; Kalvatchev, Nikolay ; Zeller, Herve ; Bányai, K. ; Jakab, F. / Serologic evidence of Crimean-Congo hemorrhagic fever virus infection in Hungary. In: Vector-Borne and Zoonotic Diseases. 2013 ; Vol. 13, No. 4. pp. 270-272.
@article{8c6c89b0b7234daba8304f49589faf8e,
title = "Serologic evidence of Crimean-Congo hemorrhagic fever virus infection in Hungary",
abstract = "Crimean-Congo hemorrhagic fever virus (CCHFV) is a typical tick-borne pathogen that causes an increasing number of severe infections in many parts of Africa, Asia, the Middle East, and the Balkans, as well as in some other parts of Europe. The virus is transmitted primarily by Hyalomma spp., and the spectrum of natural hosts for CCHFV is broad, including wild and domestic animals. Although, the presence of CCHFV was hypothesized in Hungary, no significant research activity has been carried out in the past 30 years. In the present study, we provide serological evidence of CCHFV infection in Lepus europeus using newly developed antibody detection assays. Of 198 samples, 12 (6{\%}) were positive for immunoglobulin G antibody against CCHFV, with 2 independent detection assays. This observation indicates a need for a large-scale surveillance to estimate the potential public health risk of CCHFV in Hungary.",
keywords = "Crimean-Congo hemorrhagic fever virus, Enzymelinkedimmunosorbent assay, European brown hare, Hungary., Transgenic cell line",
author = "Vikt{\'o}ria N{\'e}meth and Mikl{\'o}s Oldal and L. Egyed and Mikl{\'o}s Gyuranecz and K. Erd{\'e}lyi and K. Kvell and Nikolay Kalvatchev and Herve Zeller and K. B{\'a}nyai and F. Jakab",
year = "2013",
month = "4",
day = "1",
doi = "10.1089/vbz.2012.1011",
language = "English",
volume = "13",
pages = "270--272",
journal = "Vector-Borne and Zoonotic Diseases",
issn = "1530-3667",
publisher = "Mary Ann Liebert Inc.",
number = "4",

}

TY - JOUR

T1 - Serologic evidence of Crimean-Congo hemorrhagic fever virus infection in Hungary

AU - Németh, Viktória

AU - Oldal, Miklós

AU - Egyed, L.

AU - Gyuranecz, Miklós

AU - Erdélyi, K.

AU - Kvell, K.

AU - Kalvatchev, Nikolay

AU - Zeller, Herve

AU - Bányai, K.

AU - Jakab, F.

PY - 2013/4/1

Y1 - 2013/4/1

N2 - Crimean-Congo hemorrhagic fever virus (CCHFV) is a typical tick-borne pathogen that causes an increasing number of severe infections in many parts of Africa, Asia, the Middle East, and the Balkans, as well as in some other parts of Europe. The virus is transmitted primarily by Hyalomma spp., and the spectrum of natural hosts for CCHFV is broad, including wild and domestic animals. Although, the presence of CCHFV was hypothesized in Hungary, no significant research activity has been carried out in the past 30 years. In the present study, we provide serological evidence of CCHFV infection in Lepus europeus using newly developed antibody detection assays. Of 198 samples, 12 (6%) were positive for immunoglobulin G antibody against CCHFV, with 2 independent detection assays. This observation indicates a need for a large-scale surveillance to estimate the potential public health risk of CCHFV in Hungary.

AB - Crimean-Congo hemorrhagic fever virus (CCHFV) is a typical tick-borne pathogen that causes an increasing number of severe infections in many parts of Africa, Asia, the Middle East, and the Balkans, as well as in some other parts of Europe. The virus is transmitted primarily by Hyalomma spp., and the spectrum of natural hosts for CCHFV is broad, including wild and domestic animals. Although, the presence of CCHFV was hypothesized in Hungary, no significant research activity has been carried out in the past 30 years. In the present study, we provide serological evidence of CCHFV infection in Lepus europeus using newly developed antibody detection assays. Of 198 samples, 12 (6%) were positive for immunoglobulin G antibody against CCHFV, with 2 independent detection assays. This observation indicates a need for a large-scale surveillance to estimate the potential public health risk of CCHFV in Hungary.

KW - Crimean-Congo hemorrhagic fever virus

KW - Enzymelinkedimmunosorbent assay

KW - European brown hare

KW - Hungary.

KW - Transgenic cell line

UR - http://www.scopus.com/inward/record.url?scp=84875705216&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84875705216&partnerID=8YFLogxK

U2 - 10.1089/vbz.2012.1011

DO - 10.1089/vbz.2012.1011

M3 - Article

C2 - 23421895

AN - SCOPUS:84875705216

VL - 13

SP - 270

EP - 272

JO - Vector-Borne and Zoonotic Diseases

JF - Vector-Borne and Zoonotic Diseases

SN - 1530-3667

IS - 4

ER -