Serial measurement of circulating immune complexes in myocardial infarction

E. Szondy, Z. Mezey, G. Füst, J. Székely, S. Gerö

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

To study the changes in the quantity of circulating immune complexes in myocardial infarction two serial investigations were performed in 45 and 63 patients, respectively. For the detection of circulating immune complexes in the first series, two methods, a complement consumption test and a Clq-solubility test were used. In the second series, a polyethylene glycol (PEG) precipitation assay was added to these methods. The incidence of circulating immune complexes was studied on the first, third, seventh, 14th, and 21st day. On the first day the complexes were detected in 59% of the patients. Their occurrence increased in the further samplings to 77%, but from the seventh day their concentration decreased and on the 21st day they were detected in 63%. Three types of changes in the level of circulating immune complexes could be shown. In type I immune complexes were detected in the first day after the onset of the infarction, then, after a gradual decrease, the results became negative. In type II immune complexes appeared in the second to third week and their quantity did not alter during the entire observation period. In type III the circulating immune complexes could be detected throughout the whole period of the study. These changes in their concentration were frequently associated with the clinical course of the disease.

Original languageEnglish
Pages (from-to)93-98
Number of pages6
JournalBritish Heart Journal
Volume46
Issue number1
Publication statusPublished - 1981

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Antigen-Antibody Complex
Myocardial Infarction
Solubility
Infarction
Observation
Incidence

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Szondy, E., Mezey, Z., Füst, G., Székely, J., & Gerö, S. (1981). Serial measurement of circulating immune complexes in myocardial infarction. British Heart Journal, 46(1), 93-98.

Serial measurement of circulating immune complexes in myocardial infarction. / Szondy, E.; Mezey, Z.; Füst, G.; Székely, J.; Gerö, S.

In: British Heart Journal, Vol. 46, No. 1, 1981, p. 93-98.

Research output: Contribution to journalArticle

Szondy, E, Mezey, Z, Füst, G, Székely, J & Gerö, S 1981, 'Serial measurement of circulating immune complexes in myocardial infarction', British Heart Journal, vol. 46, no. 1, pp. 93-98.
Szondy, E. ; Mezey, Z. ; Füst, G. ; Székely, J. ; Gerö, S. / Serial measurement of circulating immune complexes in myocardial infarction. In: British Heart Journal. 1981 ; Vol. 46, No. 1. pp. 93-98.
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