Serial and triadic synapses in the cerebellar nuclei of the cat

J. Hámori, E. Mezey

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A quantitative electron microscopic investigation of the nucleus interpositus in cat cerebellum reveals that about 1.5% of all observed synapses are established between synaptic vesicle-bearing profiles. It is shown by serial sections that 70% of these synaptic complexes are triadic arrangements and 30% are serial synapses. Further analysis discloses that the first presynaptic element in the triadic and serial synapses may be one of four different axonal types: (A) Purkinje-cell axons; (B) and (C) afferent fibers containing large round vesicles and originating from the brain stem (probably mossy and climbing fiber collaterals); and (D) axon terminals containing small round vesicles. Indirect evidence suggests that type D profiles are the recurrent axon collaterals of the projective neurons. The second, postsynaptic and presynaptic, vesicle-bearing process in these complexes is either a class D terminal, or a somewhat more "dendrite-like" profile (Class E) containing flattened vesicles, and identified as belonging to processes of local Golgi type II interneurons.

Original languageEnglish
Pages (from-to)259-273
Number of pages15
JournalExperimental Brain Research
Volume30
Issue number2-3
DOIs
Publication statusPublished - Nov 1977

Fingerprint

Cerebellar Nuclei
Synapses
Cats
Axons
Synaptic Vesicles
Purkinje Cells
Presynaptic Terminals
Interneurons
Dendrites
Cerebellum
Brain Stem
Electrons
Neurons

Keywords

  • Cerebellum
  • Nuclei
  • Triadic synapses

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Serial and triadic synapses in the cerebellar nuclei of the cat. / Hámori, J.; Mezey, E.

In: Experimental Brain Research, Vol. 30, No. 2-3, 11.1977, p. 259-273.

Research output: Contribution to journalArticle

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