Sequence determination of actagardine, a novel lantibiotic, by homonuclear 2D NMR spectroscopy

J. K. Kettenring, A. Malabarba, K. Vékey, B. Cavalleri

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

By combination of several 1H NMR techniques, the sequence of actagardine has been elucidated. It has been shown that it is a tetracyclic 19-residue peptide antibiotic. It differs from the previously described lanthionine-containing peptide antibiotics belonging to the lantibiotic class.

Original languageEnglish
Pages (from-to)1082-1088
Number of pages7
JournalJournal of Antibiotics
Volume43
Issue number9
Publication statusPublished - 1990

Fingerprint

Bacteriocins
Sequence Analysis
Magnetic Resonance Spectroscopy
Anti-Bacterial Agents
Peptides
gardimycin
Proton Magnetic Resonance Spectroscopy
lanthionine

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology

Cite this

Sequence determination of actagardine, a novel lantibiotic, by homonuclear 2D NMR spectroscopy. / Kettenring, J. K.; Malabarba, A.; Vékey, K.; Cavalleri, B.

In: Journal of Antibiotics, Vol. 43, No. 9, 1990, p. 1082-1088.

Research output: Contribution to journalArticle

Kettenring, JK, Malabarba, A, Vékey, K & Cavalleri, B 1990, 'Sequence determination of actagardine, a novel lantibiotic, by homonuclear 2D NMR spectroscopy', Journal of Antibiotics, vol. 43, no. 9, pp. 1082-1088.
Kettenring, J. K. ; Malabarba, A. ; Vékey, K. ; Cavalleri, B. / Sequence determination of actagardine, a novel lantibiotic, by homonuclear 2D NMR spectroscopy. In: Journal of Antibiotics. 1990 ; Vol. 43, No. 9. pp. 1082-1088.
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