Separation of strength and selectivity of mobile phase by spectral mapping technique

E. Forgács, T. Cserháti, Sándor Balogh, Roman Kaliszan, Peter Haber, Anton Nasal

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The retention behaviour of seven monotetrazolium and nine ditetrazolium salts was studied in seven different mobile phases on alumina and impregnated alumina stationary phases. The strength and selectivity of the components of mobile phases were separately calculated by the spectral mapping technique. It was established that tetrahydrofuran (THF) has the highest solvent strength while the differences among ethanol, 1-propanol, 2-propanol and dioxane were relatively low. The selectivity of THF was also considerably different from those of other solvents. Hydrophobicity and electronic parameters were equally involved in the retention strength and selectivity of tetrazolium salts, indicating the mixed character of their interaction with the alumina stationary phase.

Original languageEnglish
Pages (from-to)348-355
Number of pages8
JournalBiomedical Chromatography
Volume15
Issue number5
DOIs
Publication statusPublished - 2001

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Aluminum Oxide
Tetrazolium Salts
1-Propanol
2-Propanol
Hydrophobicity
Hydrophobic and Hydrophilic Interactions
Ethanol
Salts
tetrahydrofuran

ASJC Scopus subject areas

  • Analytical Chemistry
  • Clinical Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Pharmacology

Cite this

Separation of strength and selectivity of mobile phase by spectral mapping technique. / Forgács, E.; Cserháti, T.; Balogh, Sándor; Kaliszan, Roman; Haber, Peter; Nasal, Anton.

In: Biomedical Chromatography, Vol. 15, No. 5, 2001, p. 348-355.

Research output: Contribution to journalArticle

Forgács, E. ; Cserháti, T. ; Balogh, Sándor ; Kaliszan, Roman ; Haber, Peter ; Nasal, Anton. / Separation of strength and selectivity of mobile phase by spectral mapping technique. In: Biomedical Chromatography. 2001 ; Vol. 15, No. 5. pp. 348-355.
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