Separation of sesquiterpenes from Yarrow (Achillea millefolium L. s. l.) by LC-MS on non-porous columns

Gergely Montsko, Borbala Boros, Aniko Takatsy, R. Ohmacht, Sabine Glasl, Liselotte Krenn, L. Márk, Gottfried Reznicek

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Species of the genus Achillea have been used in traditional folk medicine for centuries. In Europe taxa of the Achillea millefolium group are widely spread, their correct taxonomic differentiation by morphological and anatomical characteristics encounters some difficulties. Several species of the polyploid A. millefolium group however, can be characterised by their distinct sesquiterpene pattern. Analysis is usually performed by LC using conventional RP stationary phases. Likewise, it has been proven that non-porous RP stationary phases are an excellent alternative for sensitive and more rapid separations of plant extracts. In the present work a Kovasil MS-C18 1.5 μm non-porous packing was used with an acetonitrile-water gradient for the analysis of Achillea flower extracts. Detection and identification of the respective sesquiterpenes has been achieved by diode array detection and LC coupled APCI+ and ESI+ mass spectrometry.

Original languageEnglish
Pages (from-to)467-470
Number of pages4
JournalChromatographia
Volume67
Issue number5-6
DOIs
Publication statusPublished - Mar 2008

Fingerprint

Achillea
Sesquiterpenes
Plant Extracts
Traditional Medicine
Medicine
Mass spectrometry
Diodes
Polyploidy
Electrospray Ionization Mass Spectrometry
Water

Keywords

  • Achillea millefolium
  • Column liquid chromatography-mass spectrometry
  • Non-porous stationary phases
  • Sesquiterpene

ASJC Scopus subject areas

  • Analytical Chemistry
  • Clinical Biochemistry

Cite this

Separation of sesquiterpenes from Yarrow (Achillea millefolium L. s. l.) by LC-MS on non-porous columns. / Montsko, Gergely; Boros, Borbala; Takatsy, Aniko; Ohmacht, R.; Glasl, Sabine; Krenn, Liselotte; Márk, L.; Reznicek, Gottfried.

In: Chromatographia, Vol. 67, No. 5-6, 03.2008, p. 467-470.

Research output: Contribution to journalArticle

Montsko, Gergely ; Boros, Borbala ; Takatsy, Aniko ; Ohmacht, R. ; Glasl, Sabine ; Krenn, Liselotte ; Márk, L. ; Reznicek, Gottfried. / Separation of sesquiterpenes from Yarrow (Achillea millefolium L. s. l.) by LC-MS on non-porous columns. In: Chromatographia. 2008 ; Vol. 67, No. 5-6. pp. 467-470.
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