Separation of enantiomers by supercritical fluid extraction

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The purpose of the present study is to demonstrate the applicability of SFE for the separation of enantiomeric acid mixtures. (±)-cis- and (±)-trans-permetric acids were resolved with R-(+)-α-phenylethylamine and S-(+)-2-benzylaminobutan-1-ol, respectively. The effects of temperature and pressure on the quantity and quality of cis- and trans-acid resolution products are demonstrated. Partial resolutions of the acids were investigated in the range 100-200 bar and 33-47°C by designed experiments.

Original languageEnglish
Pages (from-to)331-336
Number of pages6
JournalJournal of Supercritical Fluids
Volume13
Issue number1-3
DOIs
Publication statusPublished - Jun 15 1998

Keywords

  • Enantiomer
  • Experimental design
  • Racemate
  • Resolution
  • Supercritical extraction

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

Fingerprint Dive into the research topics of 'Separation of enantiomers by supercritical fluid extraction'. Together they form a unique fingerprint.

  • Cite this