Separation of cypermethrin diastereomers by normal phase liquid chromatography

Cs Hegyi, E. Olah, J. Fekete, G. Szainik

Research output: Contribution to journalArticle


Insecticides cause great environmental problems. We studied the separation of cypermethrin diastereomers. Cypermethrin has three asymmetric carbon atoms; it has four diastereomers. Research with reversed phase high performance liquid chromatography was unsuccessful. For the separation, we applied normal phase high performance liquid chromatography. In a systematic study, the best column was selected and the mobile phase was optimized. When we used acetonitrile as a polar modifier in the mobile phase, we found that the behaviour of acetonitrile is different in the separation of the four diastereomers from the other modifiers.

Original languageEnglish
Pages (from-to)2835-2851
Number of pages17
JournalJournal of Liquid Chromatography and Related Technologies
Issue number19
Publication statusPublished - Nov 1 2006



  • Acetonitrile
  • Cypermethrin
  • Diastereomers
  • NPLC
  • Organic modifiers

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Pharmaceutical Science
  • Clinical Biochemistry

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