Separation of cypermethrin diastereomers by normal phase liquid chromatography

Cs Hegyi, E. Olah, J. Fekete, G. Szainik

Research output: Contribution to journalArticle

Abstract

Insecticides cause great environmental problems. We studied the separation of cypermethrin diastereomers. Cypermethrin has three asymmetric carbon atoms; it has four diastereomers. Research with reversed phase high performance liquid chromatography was unsuccessful. For the separation, we applied normal phase high performance liquid chromatography. In a systematic study, the best column was selected and the mobile phase was optimized. When we used acetonitrile as a polar modifier in the mobile phase, we found that the behaviour of acetonitrile is different in the separation of the four diastereomers from the other modifiers.

Original languageEnglish
Pages (from-to)2835-2851
Number of pages17
JournalJournal of Liquid Chromatography and Related Technologies
Volume29
Issue number19
DOIs
Publication statusPublished - Nov 1 2006

Fingerprint

Liquid chromatography
Liquid Chromatography
High Pressure Liquid Chromatography
High performance liquid chromatography
Reverse-Phase Chromatography
Insecticides
Carbon
Research
Atoms
cypermethrin
acetonitrile

Keywords

  • Acetonitrile
  • Cypermethrin
  • Diastereomers
  • NPLC
  • Organic modifiers

ASJC Scopus subject areas

  • Analytical Chemistry
  • Clinical Biochemistry

Cite this

Separation of cypermethrin diastereomers by normal phase liquid chromatography. / Hegyi, Cs; Olah, E.; Fekete, J.; Szainik, G.

In: Journal of Liquid Chromatography and Related Technologies, Vol. 29, No. 19, 01.11.2006, p. 2835-2851.

Research output: Contribution to journalArticle

@article{ef61ee1498f14404bf02c8ad1f31477b,
title = "Separation of cypermethrin diastereomers by normal phase liquid chromatography",
abstract = "Insecticides cause great environmental problems. We studied the separation of cypermethrin diastereomers. Cypermethrin has three asymmetric carbon atoms; it has four diastereomers. Research with reversed phase high performance liquid chromatography was unsuccessful. For the separation, we applied normal phase high performance liquid chromatography. In a systematic study, the best column was selected and the mobile phase was optimized. When we used acetonitrile as a polar modifier in the mobile phase, we found that the behaviour of acetonitrile is different in the separation of the four diastereomers from the other modifiers.",
keywords = "Acetonitrile, Cypermethrin, Diastereomers, NPLC, Organic modifiers",
author = "Cs Hegyi and E. Olah and J. Fekete and G. Szainik",
year = "2006",
month = "11",
day = "1",
doi = "10.1080/10826070600959401",
language = "English",
volume = "29",
pages = "2835--2851",
journal = "Journal of Liquid Chromatography and Related Technologies",
issn = "1082-6076",
publisher = "Taylor and Francis Ltd.",
number = "19",

}

TY - JOUR

T1 - Separation of cypermethrin diastereomers by normal phase liquid chromatography

AU - Hegyi, Cs

AU - Olah, E.

AU - Fekete, J.

AU - Szainik, G.

PY - 2006/11/1

Y1 - 2006/11/1

N2 - Insecticides cause great environmental problems. We studied the separation of cypermethrin diastereomers. Cypermethrin has three asymmetric carbon atoms; it has four diastereomers. Research with reversed phase high performance liquid chromatography was unsuccessful. For the separation, we applied normal phase high performance liquid chromatography. In a systematic study, the best column was selected and the mobile phase was optimized. When we used acetonitrile as a polar modifier in the mobile phase, we found that the behaviour of acetonitrile is different in the separation of the four diastereomers from the other modifiers.

AB - Insecticides cause great environmental problems. We studied the separation of cypermethrin diastereomers. Cypermethrin has three asymmetric carbon atoms; it has four diastereomers. Research with reversed phase high performance liquid chromatography was unsuccessful. For the separation, we applied normal phase high performance liquid chromatography. In a systematic study, the best column was selected and the mobile phase was optimized. When we used acetonitrile as a polar modifier in the mobile phase, we found that the behaviour of acetonitrile is different in the separation of the four diastereomers from the other modifiers.

KW - Acetonitrile

KW - Cypermethrin

KW - Diastereomers

KW - NPLC

KW - Organic modifiers

UR - http://www.scopus.com/inward/record.url?scp=33750466164&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750466164&partnerID=8YFLogxK

U2 - 10.1080/10826070600959401

DO - 10.1080/10826070600959401

M3 - Article

AN - SCOPUS:33750466164

VL - 29

SP - 2835

EP - 2851

JO - Journal of Liquid Chromatography and Related Technologies

JF - Journal of Liquid Chromatography and Related Technologies

SN - 1082-6076

IS - 19

ER -