Sentinel lymph node detection in canine oncological patients

Lajos Balogh, Juliana Thuróczy, Gábor Andócs, Domokos Máthé, Pradip Chaudhari, Edina Perge, Imre Biksi, András Polyák, Réka Király, Gyõzõ A. Jánoki

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16 Citations (Scopus)

Abstract

Background: Sentinel lymph node detection was investigated in dogs with spontaneously occurring tumours. Material and Methods: In this pilot study, 24 client-owned spontaneously tumorous dogs presented for sentinel lymph node detection. A multiple method was used with a nuclear medicine technique (injection of 99mTc human serum albumin colloid) with scintigraphy and intraoperative guidance, and blue dye injection. Results: Of the 35 lymph nodes histologically demonstrated to contain metastases, 34 (97%) were found by radioguided surgery, which means that one would have been missed in the intraoperative localisation process; 31 nodes (89%) were clearly visualised in the gamma camera images; only 27 (77%) were blue-stained by vital dye; a mere 8 lymph nodes (23%) were enlarged and therefore easily detectable by palpation. Conclusions: Data obtained from the harmless application of the sentinel node concept are useful for the radiopharmaceutist. The sentinel lymph node concept is well applicable in the veterinary clinic.

Original languageEnglish
Pages (from-to)139-144
Number of pages6
JournalNuclear Medicine Review
Volume5
Issue number2
Publication statusPublished - Dec 1 2002

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Keywords

  • Naturally occuring canine tumours
  • Sentinel lymph node detection
  • Spontaneous animal model
  • Tc HSA colloid

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Balogh, L., Thuróczy, J., Andócs, G., Máthé, D., Chaudhari, P., Perge, E., Biksi, I., Polyák, A., Király, R., & Jánoki, G. A. (2002). Sentinel lymph node detection in canine oncological patients. Nuclear Medicine Review, 5(2), 139-144.