Sensory profiles as potential mediators of the association between hypomania and hopelessness in 488 major affective outpatients

Batya Engel-Yeger, Xenia Gonda, Giovanna Canepa, Maurizio Pompili, Zoltan Rihmer, Mario Amore, Gianluca Serafini

Research output: Contribution to journalArticle

Abstract

Introduction Extreme sensory processing patterns may contribute to the pathophysiology of major affective disorders. We aimed to examine whether significant correlations exist between sensory profiles, hypomania, self-reported depression, and hopelessness and whether sensory profiles may be potential mediators of the association between hypomania and depression/hopelessness. Methods The sample consisted of 488 euthymic affective disorder patients of which 283 diagnosed with unipolar and 162 with bipolar disorder with an age ranging from 18 to 65 years (mean = 47.82 ± 11.67). Results Lower registration of sensory input and sensory sensitivity significantly correlated with elevated self-reported depression, hopelessness, and irritable/risk-taking hypomania while sensation seeking and avoiding significantly correlated with elevated depression and hopelessness but not with irritable/risk-taking hypomania. Moreover, individuals with lower ability to register sensory input and higher hypomania showed higher self-reported depression than those with good registration of sensory information. According to SEM analyses, there was both a direct/indirect effect of irritable/risk-taking on depression-hopelessness with the mediation model explaining 48% of the variance in depression-hopelessness. Limitations The relatively small sample size and the cross-sectional nature of the study design do not allow the generalization of the main findings. Conclusion Low registration was associated with enhanced depressed mood and hopelessness while sensory seeking may be considered a resilient factor.

Original languageEnglish
Pages (from-to)466-473
Number of pages8
JournalJournal of Affective Disorders
Volume225
DOIs
Publication statusPublished - Jan 1 2018

Fingerprint

Outpatients
Depression
Risk-Taking
Mood Disorders
Aptitude
Bipolar Disorder
Sample Size
Cross-Sectional Studies

Keywords

  • Hopelessness
  • Hypomania
  • Major affective disorders
  • Self-reported depression
  • Sensory processing patterns

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Sensory profiles as potential mediators of the association between hypomania and hopelessness in 488 major affective outpatients. / Engel-Yeger, Batya; Gonda, Xenia; Canepa, Giovanna; Pompili, Maurizio; Rihmer, Zoltan; Amore, Mario; Serafini, Gianluca.

In: Journal of Affective Disorders, Vol. 225, 01.01.2018, p. 466-473.

Research output: Contribution to journalArticle

Engel-Yeger, Batya ; Gonda, Xenia ; Canepa, Giovanna ; Pompili, Maurizio ; Rihmer, Zoltan ; Amore, Mario ; Serafini, Gianluca. / Sensory profiles as potential mediators of the association between hypomania and hopelessness in 488 major affective outpatients. In: Journal of Affective Disorders. 2018 ; Vol. 225. pp. 466-473.
@article{85acda39a65d4cf9805ac9d36e382071,
title = "Sensory profiles as potential mediators of the association between hypomania and hopelessness in 488 major affective outpatients",
abstract = "Introduction Extreme sensory processing patterns may contribute to the pathophysiology of major affective disorders. We aimed to examine whether significant correlations exist between sensory profiles, hypomania, self-reported depression, and hopelessness and whether sensory profiles may be potential mediators of the association between hypomania and depression/hopelessness. Methods The sample consisted of 488 euthymic affective disorder patients of which 283 diagnosed with unipolar and 162 with bipolar disorder with an age ranging from 18 to 65 years (mean = 47.82 ± 11.67). Results Lower registration of sensory input and sensory sensitivity significantly correlated with elevated self-reported depression, hopelessness, and irritable/risk-taking hypomania while sensation seeking and avoiding significantly correlated with elevated depression and hopelessness but not with irritable/risk-taking hypomania. Moreover, individuals with lower ability to register sensory input and higher hypomania showed higher self-reported depression than those with good registration of sensory information. According to SEM analyses, there was both a direct/indirect effect of irritable/risk-taking on depression-hopelessness with the mediation model explaining 48{\%} of the variance in depression-hopelessness. Limitations The relatively small sample size and the cross-sectional nature of the study design do not allow the generalization of the main findings. Conclusion Low registration was associated with enhanced depressed mood and hopelessness while sensory seeking may be considered a resilient factor.",
keywords = "Hopelessness, Hypomania, Major affective disorders, Self-reported depression, Sensory processing patterns",
author = "Batya Engel-Yeger and Xenia Gonda and Giovanna Canepa and Maurizio Pompili and Zoltan Rihmer and Mario Amore and Gianluca Serafini",
year = "2018",
month = "1",
day = "1",
doi = "10.1016/j.jad.2017.08.036",
language = "English",
volume = "225",
pages = "466--473",
journal = "Journal of Affective Disorders",
issn = "0165-0327",
publisher = "Elsevier",

}

TY - JOUR

T1 - Sensory profiles as potential mediators of the association between hypomania and hopelessness in 488 major affective outpatients

AU - Engel-Yeger, Batya

AU - Gonda, Xenia

AU - Canepa, Giovanna

AU - Pompili, Maurizio

AU - Rihmer, Zoltan

AU - Amore, Mario

AU - Serafini, Gianluca

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Introduction Extreme sensory processing patterns may contribute to the pathophysiology of major affective disorders. We aimed to examine whether significant correlations exist between sensory profiles, hypomania, self-reported depression, and hopelessness and whether sensory profiles may be potential mediators of the association between hypomania and depression/hopelessness. Methods The sample consisted of 488 euthymic affective disorder patients of which 283 diagnosed with unipolar and 162 with bipolar disorder with an age ranging from 18 to 65 years (mean = 47.82 ± 11.67). Results Lower registration of sensory input and sensory sensitivity significantly correlated with elevated self-reported depression, hopelessness, and irritable/risk-taking hypomania while sensation seeking and avoiding significantly correlated with elevated depression and hopelessness but not with irritable/risk-taking hypomania. Moreover, individuals with lower ability to register sensory input and higher hypomania showed higher self-reported depression than those with good registration of sensory information. According to SEM analyses, there was both a direct/indirect effect of irritable/risk-taking on depression-hopelessness with the mediation model explaining 48% of the variance in depression-hopelessness. Limitations The relatively small sample size and the cross-sectional nature of the study design do not allow the generalization of the main findings. Conclusion Low registration was associated with enhanced depressed mood and hopelessness while sensory seeking may be considered a resilient factor.

AB - Introduction Extreme sensory processing patterns may contribute to the pathophysiology of major affective disorders. We aimed to examine whether significant correlations exist between sensory profiles, hypomania, self-reported depression, and hopelessness and whether sensory profiles may be potential mediators of the association between hypomania and depression/hopelessness. Methods The sample consisted of 488 euthymic affective disorder patients of which 283 diagnosed with unipolar and 162 with bipolar disorder with an age ranging from 18 to 65 years (mean = 47.82 ± 11.67). Results Lower registration of sensory input and sensory sensitivity significantly correlated with elevated self-reported depression, hopelessness, and irritable/risk-taking hypomania while sensation seeking and avoiding significantly correlated with elevated depression and hopelessness but not with irritable/risk-taking hypomania. Moreover, individuals with lower ability to register sensory input and higher hypomania showed higher self-reported depression than those with good registration of sensory information. According to SEM analyses, there was both a direct/indirect effect of irritable/risk-taking on depression-hopelessness with the mediation model explaining 48% of the variance in depression-hopelessness. Limitations The relatively small sample size and the cross-sectional nature of the study design do not allow the generalization of the main findings. Conclusion Low registration was associated with enhanced depressed mood and hopelessness while sensory seeking may be considered a resilient factor.

KW - Hopelessness

KW - Hypomania

KW - Major affective disorders

KW - Self-reported depression

KW - Sensory processing patterns

UR - http://www.scopus.com/inward/record.url?scp=85028509612&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85028509612&partnerID=8YFLogxK

U2 - 10.1016/j.jad.2017.08.036

DO - 10.1016/j.jad.2017.08.036

M3 - Article

VL - 225

SP - 466

EP - 473

JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

SN - 0165-0327

ER -