Self-regulation of the lipid content of membranes by non-bilayer lipids

A hypothesis

G. Garab, Karl Lohner, Peter Laggner, T. Farkas

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Many biological membranes contain lipids that do not form a lamellar phase but the roles of these lipids are not well understood. An artificial membrane assembled from the main non-bilayer lipid and the major integral protein of pea thylakoids revealed that the protein spatially inhibits the formation of non-bilayer structures in the lamellae. Without this inhibition, excess lipids are secreted, creating lipid reservoirs for metabolism and/or later uptake. This determines the protein:lipid ratio in the membrane and hence the balance between structural flexibility and the stability of the key constituents that participate in cooperative interactions.

Original languageEnglish
Pages (from-to)489-494
Number of pages6
JournalTrends in Plant Science
Volume5
Issue number11
DOIs
Publication statusPublished - 2000

Fingerprint

Lipid A
Membrane Lipids
lipid content
Lipids
lipids
Artificial Membranes
Thylakoids
Proteins
Peas
Lipid Metabolism
artificial membranes
pea protein
thylakoids
cooperatives
Membranes
lipid A
proteins
uptake mechanisms
metabolism

ASJC Scopus subject areas

  • Genetics

Cite this

Self-regulation of the lipid content of membranes by non-bilayer lipids : A hypothesis. / Garab, G.; Lohner, Karl; Laggner, Peter; Farkas, T.

In: Trends in Plant Science, Vol. 5, No. 11, 2000, p. 489-494.

Research output: Contribution to journalArticle

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