Támadás helyett önvédelem - Immunterápia tüdõrákban

Translated title of the contribution: Self defense instead of offense - Immunotherapy in lung cancer

Judit Moldvay, G. Ostoros

Research output: Contribution to journalReview article

Abstract

Lung cancer is the leading cause of cancer death worldwide and also in Hungary, therefore new therapeutic strategies are of great importance. Among immunotherapeutic approaches immune checkpoint inhibition appears to be the most promising. Recent studies have shown efficacy of immunotherapy, especially in squamous cell lung cancer, which is a big step forward in the treatment of this histological subtype. Unlike in the molecularly targeted therapies, the patient selection method has not yet been developed, although some studies indicate the predictive value of tumor cell PD-L1 immunopositivity, especially in lung adenocarcinoma. Introduction of immunotherapy carries challenge for clinicians regarding the radiological assessment of therapeutic efficiency as well as the management of side effects of new profile. The favorable results of recent studies, however, provide hope in this malignancy still presenting a major therapeutic challenge.

Original languageHungarian
Pages (from-to)28-33
Number of pages6
JournalMagyar Onkologia
Volume60
Issue number1
Publication statusPublished - Mar 2 2016

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Immunotherapy
Lung Neoplasms
Therapeutics
Squamous Cell Neoplasms
Neoplasms
Hungary
Patient Selection
Cause of Death

ASJC Scopus subject areas

  • Oncology

Cite this

Támadás helyett önvédelem - Immunterápia tüdõrákban. / Moldvay, Judit; Ostoros, G.

In: Magyar Onkologia, Vol. 60, No. 1, 02.03.2016, p. 28-33.

Research output: Contribution to journalReview article

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