Selenium in the blood of patients with colorectal cancer and neoplastic polyp.

G. Rumi, I. Imre, C. Sülle, I. Sarudi, J. Kelemen, Z. Lassú

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Abstract

Samples of whole blood were obtained from 51 patients with newly diagnosed colorectal cancer as well as from 76 patients with neoplastic colorectal polyp, and from 30 healthy blood bank donors. Selenium was determined by the fluorimetric method. Significantly decreased selenium concentrations of blood samples from patients with colorectal cancer and villous adenoma were found. There was not any correlation between the blood selenium levels of patients with adenomatous polyp and the severity of dysplasia in removed polyps. The lowest mean selenium level in patients with villous adenoma indicates that selenium deficiency may be an important factor in the development of colorectal cancer arising from villous adenomas.

Original languageEnglish
Pages (from-to)275-279
Number of pages5
JournalActa physiologica Hungarica
Volume80
Issue number1-4
Publication statusPublished - 1992

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ASJC Scopus subject areas

  • Physiology (medical)

Cite this

Rumi, G., Imre, I., Sülle, C., Sarudi, I., Kelemen, J., & Lassú, Z. (1992). Selenium in the blood of patients with colorectal cancer and neoplastic polyp. Acta physiologica Hungarica, 80(1-4), 275-279.