Selectively monomodified cyclodextrins, synthetic strategies

Shengping Tian, Henghu Zhu, P. Forgó, Valerian T. D'Souza

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Monomodifications of cyclodextrins to give selectively 2-, 3-, or 6- substituted product is a challenging task because of the number of hydroxyl groups that can potentially react with the incoming reagent. The principles and the methods involved in manipulations of the differences in the chemistry of these hydroxyl groups to control the outcome of an electrophilic reaction with them to produce monoalkylated (ether-linkaged) cyclodextrin derivatives are discussed and illustrated.

Original languageEnglish
Pages (from-to)2624-2630
Number of pages7
JournalJournal of Organic Chemistry
Volume65
Issue number9
DOIs
Publication statusPublished - May 5 2000

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Cyclodextrins
Hydroxyl Radical
Ether

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Selectively monomodified cyclodextrins, synthetic strategies. / Tian, Shengping; Zhu, Henghu; Forgó, P.; D'Souza, Valerian T.

In: Journal of Organic Chemistry, Vol. 65, No. 9, 05.05.2000, p. 2624-2630.

Research output: Contribution to journalArticle

Tian, Shengping ; Zhu, Henghu ; Forgó, P. ; D'Souza, Valerian T. / Selectively monomodified cyclodextrins, synthetic strategies. In: Journal of Organic Chemistry. 2000 ; Vol. 65, No. 9. pp. 2624-2630.
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