Selective Synthesis of Fluorine-Containing Cyclic β-Amino Acid Scaffolds

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Fluorine-containing organic molecules have generated increasing impact in drug research over the past decade. Their preparation and development of novel synthetic methods towards new types of fluorinated molecules among them of β-amino acid derivatives has received large interest. Our research group have designed various highly selective and stereocontrolled methods for the construction of fluorine-containing cyclic β-amino acid derivatives. The synthetic approaches developed for the synthesis of various pharmacologically interesting cyclic β-amino acid derivatives as monomers with multiple stereogenic centers might be valuable protocols for the access of other classes of organic compounds.

Original languageEnglish
Pages (from-to)266-281
Number of pages16
JournalChemical Record
Volume18
Issue number3
DOIs
Publication statusPublished - Mar 1 2018

Fingerprint

Cyclic Amino Acids
Fluorine
Scaffolds
Amino acids
Derivatives
Research
Molecules
Organic compounds
Amino Acids
Monomers
Pharmaceutical Preparations

Keywords

  • amino acids
  • cyclic compounds
  • fluorine
  • selectivity
  • stereocontrol

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Chemical Engineering(all)
  • Materials Chemistry

Cite this

Selective Synthesis of Fluorine-Containing Cyclic β-Amino Acid Scaffolds. / Kiss, L.; Fülöp, F.

In: Chemical Record, Vol. 18, No. 3, 01.03.2018, p. 266-281.

Research output: Contribution to journalArticle

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