Selective synthesis of arylacetic acid esters from ethyl acetoacetate and aryl halides in the presence of copper(II) on 4 Å molecular sieves

Dávid Zsolczai, János Németh, Z. Hell

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A heterogeneous catalyst, copper(II) on 4 Å molecular sieves has successfully been used in the arylation of ethyl acetoacetate, selectively forming arylacetic esters in high yields. The air stable and easily handled catalyst can be simply filtered off during purification thus avoiding significant metal contamination of the product.

Original languageEnglish
Pages (from-to)6389-6392
Number of pages4
JournalTetrahedron Letters
Volume56
Issue number46
DOIs
Publication statusPublished - Nov 18 2015

Fingerprint

Molecular sieves
Copper
Esters
Metals
Air
Catalysts
Acids
Purification
Contamination
ethyl acetoacetate

Keywords

  • 4 Å molecular sieves
  • Arylacetic esters
  • Copper
  • Heterogeneous catalysis
  • Selective synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Selective synthesis of arylacetic acid esters from ethyl acetoacetate and aryl halides in the presence of copper(II) on 4 Å molecular sieves. / Zsolczai, Dávid; Németh, János; Hell, Z.

In: Tetrahedron Letters, Vol. 56, No. 46, 18.11.2015, p. 6389-6392.

Research output: Contribution to journalArticle

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