Selective quantitative determination of tobramycin from fermentation broth

B. Kiss Gy., V. Szell, G. Ambrus, I. Ott

Research output: Contribution to journalArticle

2 Citations (Scopus)


A derivative of Rhizobium meliloti 41 was constructed (strain GY654) which was resistant to apramycin and kanamycin but remained sensitive to tobramycin. Strain GY654 selectively measures tobramycin and 6''-O-carbamoyltobramycin in the presence of apramycin, kanamycin and 6''-O-carbamoylkanamycin B, therefore it is suitable for the rapid quantitation of 6''-O-carbamoyltobramycin and tobramycin in fermentation broths of Streptomyces tenebrarius and solvents containing antibiotic mixtures.

Original languageEnglish
Pages (from-to)89-92
Number of pages4
JournalActa microbiologica Hungarica
Issue number2
Publication statusPublished - Jan 1 1988


ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this