Selective quantitative determination of tobramycin from fermentation broth

G. Kiss, V. Szell, G. Ambrus, I. Ott

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A derivative of Rhizobium meliloti 41 was constructed (strain GY654) which was resistant to apramycin and kanamycin but remained sensitive to tobramycin. Strain GY654 selectively measures tobramycin and 6''-O-carbamoyltobramycin in the presence of apramycin, kanamycin and 6''-O-carbamoylkanamycin B, therefore it is suitable for the rapid quantitation of 6''-O-carbamoyltobramycin and tobramycin in fermentation broths of Streptomyces tenebrarius and solvents containing antibiotic mixtures.

Original languageEnglish
Pages (from-to)89-92
Number of pages4
JournalActa Microbiologica Hungarica
Volume35
Issue number2
Publication statusPublished - 1988

Fingerprint

Tobramycin
Fermentation
Kanamycin
Sinorhizobium meliloti
Streptomyces
Anti-Bacterial Agents
6''-O-carbamoyltobramycin
apramycin

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Selective quantitative determination of tobramycin from fermentation broth. / Kiss, G.; Szell, V.; Ambrus, G.; Ott, I.

In: Acta Microbiologica Hungarica, Vol. 35, No. 2, 1988, p. 89-92.

Research output: Contribution to journalArticle

Kiss, G. ; Szell, V. ; Ambrus, G. ; Ott, I. / Selective quantitative determination of tobramycin from fermentation broth. In: Acta Microbiologica Hungarica. 1988 ; Vol. 35, No. 2. pp. 89-92.
@article{c5b733245e89432494dae7f8b523ae67,
title = "Selective quantitative determination of tobramycin from fermentation broth",
abstract = "A derivative of Rhizobium meliloti 41 was constructed (strain GY654) which was resistant to apramycin and kanamycin but remained sensitive to tobramycin. Strain GY654 selectively measures tobramycin and 6''-O-carbamoyltobramycin in the presence of apramycin, kanamycin and 6''-O-carbamoylkanamycin B, therefore it is suitable for the rapid quantitation of 6''-O-carbamoyltobramycin and tobramycin in fermentation broths of Streptomyces tenebrarius and solvents containing antibiotic mixtures.",
author = "G. Kiss and V. Szell and G. Ambrus and I. Ott",
year = "1988",
language = "English",
volume = "35",
pages = "89--92",
journal = "Acta Microbiologica et Immunologica Hungarica",
issn = "1217-8950",
publisher = "Akademiai Kiado",
number = "2",

}

TY - JOUR

T1 - Selective quantitative determination of tobramycin from fermentation broth

AU - Kiss, G.

AU - Szell, V.

AU - Ambrus, G.

AU - Ott, I.

PY - 1988

Y1 - 1988

N2 - A derivative of Rhizobium meliloti 41 was constructed (strain GY654) which was resistant to apramycin and kanamycin but remained sensitive to tobramycin. Strain GY654 selectively measures tobramycin and 6''-O-carbamoyltobramycin in the presence of apramycin, kanamycin and 6''-O-carbamoylkanamycin B, therefore it is suitable for the rapid quantitation of 6''-O-carbamoyltobramycin and tobramycin in fermentation broths of Streptomyces tenebrarius and solvents containing antibiotic mixtures.

AB - A derivative of Rhizobium meliloti 41 was constructed (strain GY654) which was resistant to apramycin and kanamycin but remained sensitive to tobramycin. Strain GY654 selectively measures tobramycin and 6''-O-carbamoyltobramycin in the presence of apramycin, kanamycin and 6''-O-carbamoylkanamycin B, therefore it is suitable for the rapid quantitation of 6''-O-carbamoyltobramycin and tobramycin in fermentation broths of Streptomyces tenebrarius and solvents containing antibiotic mixtures.

UR - http://www.scopus.com/inward/record.url?scp=0023720390&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023720390&partnerID=8YFLogxK

M3 - Article

C2 - 3188834

AN - SCOPUS:0023720390

VL - 35

SP - 89

EP - 92

JO - Acta Microbiologica et Immunologica Hungarica

JF - Acta Microbiologica et Immunologica Hungarica

SN - 1217-8950

IS - 2

ER -