Selecting Resolving Agents with Respect to Their Eutectic Compositions

Zsolt Szeleczky, Sándor Semsey, Péter Bagi, Emese Pálovics, F. Faigl, E. Fogassy

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In order to develop a resolution procedure for a given racemic compound, the first and the most important step is finding the most suitable resolving agent. We studied 18 individual resolutions that were carried out with resolving agents having high eutectic composition. We found that very high enantiomeric excess values were obtained in all cases. We assume that the eutectic composition of a given resolving agent is one of the most important properties that should always be considered during the search for the most efficient resolving agent. Chirality 28:230-234, 2016.

Original languageEnglish
Pages (from-to)230-234
Number of pages5
JournalChirality
Volume28
Issue number3
DOIs
Publication statusPublished - Mar 1 2016

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Eutectics
Chemical analysis
Chirality

Keywords

  • classical resolution
  • diastereomeric salt
  • enantiomeric mixture
  • eutectic composition
  • resolving agent

ASJC Scopus subject areas

  • Organic Chemistry
  • Analytical Chemistry
  • Drug Discovery
  • Pharmacology
  • Catalysis
  • Spectroscopy

Cite this

Selecting Resolving Agents with Respect to Their Eutectic Compositions. / Szeleczky, Zsolt; Semsey, Sándor; Bagi, Péter; Pálovics, Emese; Faigl, F.; Fogassy, E.

In: Chirality, Vol. 28, No. 3, 01.03.2016, p. 230-234.

Research output: Contribution to journalArticle

Szeleczky, Zsolt ; Semsey, Sándor ; Bagi, Péter ; Pálovics, Emese ; Faigl, F. ; Fogassy, E. / Selecting Resolving Agents with Respect to Their Eutectic Compositions. In: Chirality. 2016 ; Vol. 28, No. 3. pp. 230-234.
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