Secretory meningioma with bone infiltration and orbital spreading

Ferenc Kálovits, Lajos Takáts, Katalin Somogyi, Ferenc Garzuly, Márton Tompa, B. Kálmán

Research output: Contribution to journalArticle


Secretory meningioma is a rare form of meningiomas which differentiates from the meningothelial subtype. It is characterized by significant peritumor edema and distinct immunohistochemical and molecular genetic profiles. We present a middle aged female patient with secretory meningioma infiltrating the orbital bone from the primary cranial base location and causing exophthalmos, features rarely described with this tumor. Surgical resection was challenging because of the associated brain swelling and rich vascularization of the tumor. Imaging and immunohistochemical studies revealed characteristic hallmarks of secretory meningioma. While histologically it was a benign tumor, due to the orbital bone and soft tissue infiltration, postoperative management of neurological sequelae was challenging. This case highlights distinctive clinical, imaging and histological features along with individual characteristics of a rare form of meningiomas.

Original languageEnglish
Pages (from-to)141-144
Number of pages4
JournalIdeggyogyaszati szemle
Issue number3-4
Publication statusPublished - Mar 30 2019


  • bone infiltration
  • edema
  • meningioma
  • orbital spreading
  • secretory meningioma

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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  • Cite this

    Kálovits, F., Takáts, L., Somogyi, K., Garzuly, F., Tompa, M., & Kálmán, B. (2019). Secretory meningioma with bone infiltration and orbital spreading. Ideggyogyaszati szemle, 72(3-4), 141-144.