Secondary structure dependent self-assembly of β-peptides into nanosized fibrils and membranes

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Abstract

(Figure Presented) In control: The secondary structure dependent self-assembly of β-peptides in solution proves that natural biopolymers are not unique in their highly structured conformational behavior. Stereochemically controlled secondary structural units of β-peptide strands and helices intrinsically self-associate into pleated-sheet sandwiches (see picture) and helix-bundle membranes, respectively.

Original languageEnglish
Pages (from-to)2396-2400
Number of pages5
JournalAngewandte Chemie - International Edition
Volume45
Issue number15
DOIs
Publication statusPublished - Apr 3 2006

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Keywords

  • Beta-peptides
  • Foldamers
  • Nanomaterials
  • Peptide mimetics
  • Self-assembly

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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