Secondary metabolites by chemical screening 14 transformation of elaiophylin in subunits of naturally occurring acid ionophores: Synthesis, anticoccidial activity and studies concerning the ionophoric properties

Peter Hammann, Gerhard Kretzschmar, Robert Klein, Wolfgang Raether, Maria Kajtár-Peredy, Achim Kröger, Frank Ditzel

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2 Citations (Scopus)

Abstract

The synthesis of the polyether subunits (8 - 11), starting from elaiophylin (1), as well as their biological properties, nmr spectra and conformational studies were described and discussed. Based upon the missing ability of potassium transport it was deduced that compounds (8 - 11) were new lead structures concerning their anticoccidial activity.

Original languageEnglish
Pages (from-to)1471-1482
Number of pages12
JournalHeterocycles
Volume32
Issue number8
DOIs
Publication statusPublished - Aug 1 1991

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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