The scanning electron microscopic picture of the normal human bronchial mucosa and the epithelial alterations in chronic bronchitis are described. In chronic bronchitis the regular arrangement of cilia disappears, their number decreases and they become shortened, with a club like formation on the end. Focal destruction of the cilia can also be seen. In the epithelium of the mucosa the number of cells without cilia increases. This is a consequence of the destruction of the cilia on one hand, and an increase of the number of mucus secreting goblet cells on the other. Alterations of the bronchial mucosa in chronic bronchitis revealed by scanning electron microscopy may play an important part in the pathogenesis and persistence of chronic bronchitis.
|Number of pages||7|
|Journal||Morphologiai es Igazsagugyi Orvosi Szemle|
|Publication status||Published - Jan 1 1975|
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