Scaling behavior in crackle sound during lung inflation

Adriano M. Alencar, Zoltán Hantos, Ferenc Peták, József Tolnai, Tibor Asztalos, Stefano Zapperi, José S. Andrade, Sergey V. Buldyrev, H. Eugene Stanley, Béla Suki

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Abstract

During slow inflation of lung lobes, we measure a sequence of short explosive transient sound waves called "crackles," each consisting of an initial spike followed by ringing. The crackle time series is irregular and intermittent, with the number of spikes of size s following a power law, n(s)∝s, with α=2.77±0.05. We develop a model of crackle wave generation and propagation in a tree structure that combines the avalanchelike opening of airway segments with the wave propagation of crackles in a tree structure. The agreement between experiments and simulations suggests that (i) the irregularities are a consequence of structural heterogeneity in the lung, (ii) the intermittent behavior is due to the avalanchelike opening, and (iii) the scaling is a result of successive attenuations acting on the sound spikes as they propagate through a cascade of bifurcations along the airway tree.

Original languageEnglish
Pages (from-to)4659-4663
Number of pages5
JournalPhysical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
Volume60
Issue number4 B
Publication statusPublished - Oct 1 1999

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ASJC Scopus subject areas

  • Statistical and Nonlinear Physics
  • Mathematical Physics
  • Condensed Matter Physics
  • Physics and Astronomy(all)

Cite this

Alencar, A. M., Hantos, Z., Peták, F., Tolnai, J., Asztalos, T., Zapperi, S., Andrade, J. S., Buldyrev, S. V., Stanley, H. E., & Suki, B. (1999). Scaling behavior in crackle sound during lung inflation. Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics, 60(4 B), 4659-4663.