Saturated heterocycles, part 257*. Preparation and structure of partially saturated isoindolo[1,2-b]-and -[2,1-a]quinazolinones

Pál Sohár, Géza Stájer, Angela E. Szabó, József Szúnyog, Gábor Bernáth

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Through the reactions of 2-carboxybenzaldehyde (1) with cis- or trans-2-amino-1-cyclohexylmethylamine (2a,b) or cis- or trans-2-amino-4-cyclohexenyl-1-methylamine (2c,d), the partially saturated isomeric isoindolo[ 1,2-6]- (3, 4, 6-8) and -[2,1-a]quinazolinones (5) were obtained. After separation, the structures of products (3-8) were established by NMR methods, including 2D-HSC DNOE and DEPT measurements. From the cis 2a, two linearly C/D cis-fused and one angularly C/D trans-fused tetracycles were formed.

Original languageEnglish
Pages (from-to)175-180
Number of pages6
JournalHeterocycles
Volume48
Issue number1
DOIs
Publication statusPublished - Jan 1 1998

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Saturated heterocycles, part 257*. Preparation and structure of partially saturated isoindolo[1,2-b]-and -[2,1-a]quinazolinones'. Together they form a unique fingerprint.

  • Cite this