Lower respiratory tract infections are the most frequent etiology of infectious disease caused death. The most patients with pneumonia or acute exacerbations of chronic bronchitis are treated as outpatients and the antibiotic treatments are introduced empirically. Hospitalised, critically ill patients with unsuccessful antibiotic therapies are candidates for invasive diagnostic procedures. Due to the potential contamination with the oropharyngeal flora and to colonisation, several invasive diagnostic techniques have been developed. In the intensive care units protected specimen brush and protected bronchoalveolar lavage are the most frequently applied procedures. The clinical efficacy of the sampling procedures is also determined by the result of the quantitative cultures. Despite the technical- microbiological-clinical efforts we still have not got any relevant data whether the sampling procedures effectively influence the outcome of the lower respiratory tract infection sufferers.
|Number of pages||5|
|Journal||Lege Artis Medicinae|
|Publication status||Published - Nov 3 1999|
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