Salvage of ischemic myocardium by CLS 2210 in the dog

A preliminary double-blind study

L. Szlavy, I. Repa, Z. Szabo, A. de Courten, H. J. Hachen

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

To assess whether a cardiac lymphagogue, CLS 2210, would reduce myocardial infarct size after coronary artery ligation studies were performed in 14 dogs. The left anterior descending coronary artery was ligated in each dog, and the dogs were randomized to either placebo or CLS 2210 treatment, which was carried on for seven days. After seven days the animals were sacrificed and the volume of infarcted myocardium was determined macroscopically on a double-blind basis, supported by histologic examination. CLS 2210 treatment resulted in a highly significant reduction in the volume of infarcted myocardium (p

Original languageEnglish
Pages (from-to)85-90
Number of pages6
JournalAngiology
Volume38
Issue number1 II
Publication statusPublished - 1987

Fingerprint

Double-Blind Method
Myocardium
Dogs
Coronary Vessels
Ligation
Myocardial Infarction
Placebos
Therapeutics
CLS 2210

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Szlavy, L., Repa, I., Szabo, Z., de Courten, A., & Hachen, H. J. (1987). Salvage of ischemic myocardium by CLS 2210 in the dog: A preliminary double-blind study. Angiology, 38(1 II), 85-90.

Salvage of ischemic myocardium by CLS 2210 in the dog : A preliminary double-blind study. / Szlavy, L.; Repa, I.; Szabo, Z.; de Courten, A.; Hachen, H. J.

In: Angiology, Vol. 38, No. 1 II, 1987, p. 85-90.

Research output: Contribution to journalArticle

Szlavy, L, Repa, I, Szabo, Z, de Courten, A & Hachen, HJ 1987, 'Salvage of ischemic myocardium by CLS 2210 in the dog: A preliminary double-blind study', Angiology, vol. 38, no. 1 II, pp. 85-90.
Szlavy, L. ; Repa, I. ; Szabo, Z. ; de Courten, A. ; Hachen, H. J. / Salvage of ischemic myocardium by CLS 2210 in the dog : A preliminary double-blind study. In: Angiology. 1987 ; Vol. 38, No. 1 II. pp. 85-90.
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