Rosette formation in acute lymphoid leukaemia

T. Revesz, R. Szigeti, D. Schuler

Research output: Contribution to journalArticle

Abstract

The capacity of leukaemic lymphoblasts and remission lymphocytes, obtained from 40 children with acute lymphoid leukaemia, to form sheep red blood cell rosettes was investigated. Lymphoblasts isolated from the peripheral blood of the patients prior to antileukaemic treatment showed greatly reduced numbers of rosette forming cells as compared to controls (4.6% vs. 27.5%). The ratio of rosette forming cells during intensive induction chemotherapy was still significantly lower than the control value (15.7%), while after the achievement of complete remission the number of RFC approximated the normal value (22.5%). The presence of leukaemic serum had no significant effect on the number of RFC.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalHaematologia
Volume9
Issue number1-2
Publication statusPublished - 1975

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Rosette Formation
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Induction Chemotherapy
Sheep
Reference Values
Erythrocytes
Lymphocytes
Serum
Therapeutics

ASJC Scopus subject areas

  • Hematology

Cite this

Revesz, T., Szigeti, R., & Schuler, D. (1975). Rosette formation in acute lymphoid leukaemia. Haematologia, 9(1-2), 35-38.

Rosette formation in acute lymphoid leukaemia. / Revesz, T.; Szigeti, R.; Schuler, D.

In: Haematologia, Vol. 9, No. 1-2, 1975, p. 35-38.

Research output: Contribution to journalArticle

Revesz, T, Szigeti, R & Schuler, D 1975, 'Rosette formation in acute lymphoid leukaemia', Haematologia, vol. 9, no. 1-2, pp. 35-38.
Revesz, T. ; Szigeti, R. ; Schuler, D. / Rosette formation in acute lymphoid leukaemia. In: Haematologia. 1975 ; Vol. 9, No. 1-2. pp. 35-38.
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