Role of proline in the imprinting developed by dipeptides - in Tetrahymena Possible role in hormone evolution

G. Csaba, P. Kovács

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9 Citations (Scopus)


The effects of proline and serine dipeptides containing phenylalanine, alanine and leucine on the behaviour of receptors of Tetrahymena were investigated. Only proline-containing dipeptides were able to develop positive imprinting, and the activity depended on which other amino acid was present in the dipeptide. In contrast to the positive imprinting effect of the dipeptides Pro-Phe and Pro-Ala, the dipeptide Pro-Pro and Pro-Leu caused negative imprinting. Serine dipeptides produced negative imprinting in all cases. The possible importance of proline in the evolution of hormone specificity is discussed.

Original languageEnglish
Pages (from-to)107-109
Number of pages3
Issue number2
Publication statusPublished - Feb 1 1994



  • Proline
  • Tetrahymena
  • hormone evolution
  • imprinting
  • receptor evolution

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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