Procalcitonin gyorsteszt szerepe az akut necrotizáló pancreatitis steril és inficiált formáinak elkülönítésében.

Translated title of the contribution: Role of procalcitonin rapid test in the differential diagnosis of uninfected and infected forms of acute pancreatitis

Roland Makay, Akos Issekutz, Péter Banga, Tibor Belágyi, A. Oláh

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We analysed the clinical value of the procalcitonin quick test (PCT-Q; BRAHMS Diagnostica, GmbH, Berlin) in infected pancreatic necrosis verified by guided fine-needle aspiration (FNA). In a prospective, controlled study the results of 24 patients were evaluated during 2001. PCT-Q test was performed in patients with necrosis verified on CT scan and/or septic symptoms. If PCT-Q test was positive or septic complication (infected necrosis or abscess) developed CT or US guided fine-needle aspiration was performed with Gram staining and bacterial culture of the sample. Positive FNA result was indication for surgery with repeated staining and bacterial culture of the surgical specimen. Septic complications of pancreatic origin developed in 12 patients. Comparing the results fine-needle aspiration was more authentic with a sensitivity of 92% and a specificity of 100%, while the sensitivity of the PCT-Q test remained 75% and its specificity 83%. Comparing abscess and infected necrosis, significantly higher procalcitonin values were detected in patients with necrosis. These results show that PCT-Q test can be a possible non-invasive method besides fine-needle aspiration. Elevated levels of procalcitonin (higher than 2 ng/ml) clearly suggest infection of the necrosis, while lower values do not exclude the possibility of local septic progression.

Original languageHungarian
Pages (from-to)31-33
Number of pages3
JournalMagyar sebészet
Volume56
Issue number1
Publication statusPublished - 2003

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Calcitonin
Pancreatitis
Fine Needle Biopsy
Differential Diagnosis
Necrosis
Abscess
Staining and Labeling
Prothrombin Time
Berlin
Prospective Studies
Infection

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Procalcitonin gyorsteszt szerepe az akut necrotizáló pancreatitis steril és inficiált formáinak elkülönítésében. / Makay, Roland; Issekutz, Akos; Banga, Péter; Belágyi, Tibor; Oláh, A.

In: Magyar sebészet, Vol. 56, No. 1, 2003, p. 31-33.

Research output: Contribution to journalArticle

Makay, Roland ; Issekutz, Akos ; Banga, Péter ; Belágyi, Tibor ; Oláh, A. / Procalcitonin gyorsteszt szerepe az akut necrotizáló pancreatitis steril és inficiált formáinak elkülönítésében. In: Magyar sebészet. 2003 ; Vol. 56, No. 1. pp. 31-33.
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