A myofibroblastok szerepe a vastagbél gyulladásos és daganatos folyamataiban

Translated title of the contribution: Role of myofibroblast in inflammatory bowel disease and tumor genesis

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Stroma cells with the microenvironment around them have primary role in the regulation of inflammation processes, conformation of tumors and development of metastasis. Myofibroblasts have essential role in inflammation processes and in the regeneration of encompassed tissue. Molecules produced by them operate the cells of the immunsystem and effect the proliferation of epithelium. Tumors can activate myofibroblasts which can lead to uncontrolled epithelium proliferation across production of changed and increased regulation ligands (such as cytokin, chemokin, chemotactic and other growth factors) and activation of stem cell. This process could lead piling of uncontrolled epithelial cells and can impact later on comformation of tumors. In this study we present an overview about of myofibroblasts and their roles in inflammation and neoplastic processes.

Original languageHungarian
Pages (from-to)597-602
Number of pages6
JournalOrvosi Hetilap
Volume150
Issue number13
DOIs
Publication statusPublished - Mar 1 2009

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Myofibroblasts
Inflammatory Bowel Diseases
Inflammation
Epithelium
Neoplastic Processes
Cellular Microenvironment
Neoplasms
Regeneration
Intercellular Signaling Peptides and Proteins
Stem Cells
Epithelial Cells
Neoplasm Metastasis
Ligands

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A myofibroblastok szerepe a vastagbél gyulladásos és daganatos folyamataiban. / Valcz, Gábor; Krenács, T.; Molnár, B.; Tulassay, Z.

In: Orvosi Hetilap, Vol. 150, No. 13, 01.03.2009, p. 597-602.

Research output: Contribution to journalArticle

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