Role of endothelin-1 in diabetes mellitus

Beatrix Sármán, Miklós Tóth, Anikó Somogyi

Research output: Contribution to journalReview article

41 Citations (Scopus)


Endothelin-1 is mainly synthesized by the vascular endothelial cells and acts on the vascular smooth muscle. Because of its vasoconstrictor and mitogenic effects it plays a role in the development of vascular disease. In diabetes mellitus atherosclerosis is accelerated. The authors summarize the available data of the role of endothelin-1 in Type 1 and 2 diabetes mellitus and the development of diabetic complication.

Original languageEnglish
Pages (from-to)171-175
Number of pages5
JournalDiabetes/Metabolism Reviews
Issue number2
Publication statusPublished - Jun 1 1998


  • Atherosclerosis
  • Diabetes mellitus
  • Endothelin-1
  • Insulin
  • Vasoregulation

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology

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