Role of endothelin-1 in diabetes mellitus

Beatrix Sármán, Miklós Tóth, A. Somogyi

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Endothelin-1 is mainly synthesized by the vascular endothelial cells and acts on the vascular smooth muscle. Because of its vasoconstrictor and mitogenic effects it plays a role in the development of vascular disease. In diabetes mellitus atherosclerosis is accelerated. The authors summarize the available data of the role of endothelin-1 in Type 1 and 2 diabetes mellitus and the development of diabetic complication.

Original languageEnglish
Pages (from-to)171-175
Number of pages5
JournalDiabetes/Metabolism Reviews
Volume14
Issue number2
DOIs
Publication statusPublished - Jun 1998

Fingerprint

Endothelin-1
Medical problems
Diabetes Mellitus
Endothelial cells
Vasoconstrictor Agents
Diabetes Complications
Type 1 Diabetes Mellitus
Vascular Diseases
Vascular Smooth Muscle
Type 2 Diabetes Mellitus
Muscle
Atherosclerosis
Endothelial Cells

Keywords

  • Atherosclerosis
  • Diabetes mellitus
  • Endothelin-1
  • Insulin
  • Vasoregulation

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Biochemistry

Cite this

Role of endothelin-1 in diabetes mellitus. / Sármán, Beatrix; Tóth, Miklós; Somogyi, A.

In: Diabetes/Metabolism Reviews, Vol. 14, No. 2, 06.1998, p. 171-175.

Research output: Contribution to journalArticle

Sármán, Beatrix ; Tóth, Miklós ; Somogyi, A. / Role of endothelin-1 in diabetes mellitus. In: Diabetes/Metabolism Reviews. 1998 ; Vol. 14, No. 2. pp. 171-175.
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