Role of chromoendoscopy in colon cancer surveillance in inflammatory bowel disease

Henrik Thorlacius, E. Tóth

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Inflammation in the intestine is a well-known risk factor for neoplastic changes in the mucosa. In fact, it has been shown that long-standing ulcerative colitis and colonic Crohn's disease have a significantly increased risk for developing colorectal cancer, although the estimates vary widely between studies. Conventional colonoscopy is effective in detecting polypoid changes in the mucosa. However, it is now generally accepted that neoplastic changes in colitis are frequently flat and depressed, which are easily missed by use of routine colonoscopy. The introduction of chromoendoscopy, especially in combination with magnifying endoscopy, has greatly advanced our means to detect and differentiate neoplastic lesions in the colorectum. Accumulating evidence-based data indicate that implementation of chromoendoscopy into colon cancer surveillance protocols for patients with inflammatory bowel disease is effective. However, the introduction of chromoendoscopy into surveillance programs requires meticulous training and further studies to compare the value of chromoendoscopy to newer endoscopic devices and techniques, such as narrow band imaging.

Original languageEnglish
Pages (from-to)911-917
Number of pages7
JournalInflammatory Bowel Diseases
Volume13
Issue number7
DOIs
Publication statusPublished - Jul 2007

Fingerprint

Colonoscopy
Inflammatory Bowel Diseases
Colonic Neoplasms
Mucous Membrane
Narrow Band Imaging
Colonic Diseases
Colitis
Ulcerative Colitis
Crohn Disease
Endoscopy
Intestines
Colorectal Neoplasms
Inflammation
Equipment and Supplies

Keywords

  • Cancer
  • Chromoendoscopy
  • Colon
  • Colonoscopy
  • IBD
  • Surveillance

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Role of chromoendoscopy in colon cancer surveillance in inflammatory bowel disease. / Thorlacius, Henrik; Tóth, E.

In: Inflammatory Bowel Diseases, Vol. 13, No. 7, 07.2007, p. 911-917.

Research output: Contribution to journalArticle

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