Risk assessment for respiratory complications in paediatric anaesthesia: A prospective cohort study

Britta S. Von Ungern-Sternberg, K. Boda, Neil A. Chambers, Claudia Rebmann, Chris Johnson, Peter D. Sly, Walid Habre

Research output: Contribution to journalArticle

231 Citations (Scopus)

Abstract

Summary Background Perioperative respiratory adverse events in children are one of the major causes of morbidity and mortality during paediatric anaesthesia. We aimed to identify associations between family history, anaesthesia management, and occurrence of perioperative respiratory adverse events. Methods We prospectively included all children who had general anaesthesia for surgical or medical interventions, elective or urgent procedures at Princess Margaret Hospital for Children, Perth, Australia, from Feb 1, 2007, to Jan 31, 2008. On the day of surgery, anaesthetists in charge of paediatric patients completed an adapted version of the International Study Group for Asthma and Allergies in Childhood questionnaire. We collected data on family medical history of asthma, atopy, allergy, upper respiratory tract infection, and passive smoking. Anaesthesia management and all perioperative respiratory adverse events were recorded. Findings 9297 questionnaires were available for analysis. A positive respiratory history (nocturnal dry cough, wheezing during exercise, wheezing more than three times in the past 12 months, or a history of present or past eczema) was associated with an increased risk for bronchospasm (relative risk [RR] 8·46, 95 CI 6·18-11·59; p

Original languageEnglish
Pages (from-to)773-783
Number of pages11
JournalThe Lancet
Volume376
Issue number9743
DOIs
Publication statusPublished - Sep 4 2010

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Cohort Studies
Anesthesia
Respiratory Sounds
Prospective Studies
Pediatrics
Hypersensitivity
Medical History Taking
Asthma
Bronchial Spasm
Tobacco Smoke Pollution
Eczema
Ambulatory Surgical Procedures
Cough
Respiratory Tract Infections
General Anesthesia
History
Exercise
Morbidity
Mortality
Surveys and Questionnaires

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Von Ungern-Sternberg, B. S., Boda, K., Chambers, N. A., Rebmann, C., Johnson, C., Sly, P. D., & Habre, W. (2010). Risk assessment for respiratory complications in paediatric anaesthesia: A prospective cohort study. The Lancet, 376(9743), 773-783. https://doi.org/10.1016/S0140-6736(10)61193-2

Risk assessment for respiratory complications in paediatric anaesthesia : A prospective cohort study. / Von Ungern-Sternberg, Britta S.; Boda, K.; Chambers, Neil A.; Rebmann, Claudia; Johnson, Chris; Sly, Peter D.; Habre, Walid.

In: The Lancet, Vol. 376, No. 9743, 04.09.2010, p. 773-783.

Research output: Contribution to journalArticle

Von Ungern-Sternberg, BS, Boda, K, Chambers, NA, Rebmann, C, Johnson, C, Sly, PD & Habre, W 2010, 'Risk assessment for respiratory complications in paediatric anaesthesia: A prospective cohort study', The Lancet, vol. 376, no. 9743, pp. 773-783. https://doi.org/10.1016/S0140-6736(10)61193-2
Von Ungern-Sternberg BS, Boda K, Chambers NA, Rebmann C, Johnson C, Sly PD et al. Risk assessment for respiratory complications in paediatric anaesthesia: A prospective cohort study. The Lancet. 2010 Sep 4;376(9743):773-783. https://doi.org/10.1016/S0140-6736(10)61193-2
Von Ungern-Sternberg, Britta S. ; Boda, K. ; Chambers, Neil A. ; Rebmann, Claudia ; Johnson, Chris ; Sly, Peter D. ; Habre, Walid. / Risk assessment for respiratory complications in paediatric anaesthesia : A prospective cohort study. In: The Lancet. 2010 ; Vol. 376, No. 9743. pp. 773-783.
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