Ring closure reactions in heterocyclic systems with implementation of Wittig and aza-Wittig reactions

G. Hajós, Ildikó Nagy

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Applications of Wittig and aza-Wittig reactions in various cyclizations reported during the past ten years are reviewed. The relevant literature is classified into two categories according to these two main approaches and, in both sections, the chemistry is exemplified according to the ring types synthesized. The chemical examples include both intramolecular ring closures and multistep procedures. Within the aza-Wittig reactions, special attention is paid to those products that can undergo electrocyclization to yield nitrogen heterocycles (e.g. pyridines or pyrimidines). In most interesting cases, the reaction mechanism of the transformations is discussed.

Original languageEnglish
Pages (from-to)39-58
Number of pages20
JournalCurrent Organic Chemistry
Volume12
Issue number1
DOIs
Publication statusPublished - Jan 2008

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Pyridines
Pyrimidines
Cyclization
Nitrogen

Keywords

  • Carbocycles
  • Cyclizations
  • Electrocyclizations
  • Intramolecular Wittig reaction
  • N-Heterocycles synthesis
  • Pyrimidine Derivatives

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Ring closure reactions in heterocyclic systems with implementation of Wittig and aza-Wittig reactions. / Hajós, G.; Nagy, Ildikó.

In: Current Organic Chemistry, Vol. 12, No. 1, 01.2008, p. 39-58.

Research output: Contribution to journalArticle

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