Right thoracoscopic sympathicotomy increases QT hysteresis during exercise in man

P. Musialek, A. Kardos, O. Fojt, I. Webb, J. Collin, J. Johnston, B. Casadei

Research output: Contribution to journalArticle

Abstract

Background: An altered adaptation of ventricular repolarisation to changes in heart rate may play an important role in arrhythmogenesis. Experiments in animals have indicated that right stellectomy might promote arrhythmias by uncoupling the QT from the RR interval response to exercise. Whether a similar phenomenon occurs in humans is not known. Methods and Results: Seven subjects (age 23-42 years), referred for thoracoscopic sympathicotomy for idiopathic hyperhydrosis, were studied before (C) and 6 weeks after right T1-2 sympathicotomy with T2 diathermy (postRS). High resolution ECG signal (Frank leads) was acquired during supine exercise at 70% V02max (Ex, 7min) and recovery (Rec, 15min), and a newly developed algorithm was employed to measure the RR and QT intervals on a beat-to-beat basis. RR and QT (ms) were increased postRS, both at rest (902±36 v 1078±58 and 373±7 v 398±9, mean±SEM, pEx-QTRec (ms), and was measured at RR=(RRRec-RREx)/2 (see Fig). PostRS ΔQT was markedly higher than ΔQT at C (71±6 v 39±4, p

Original languageEnglish
JournalHeart
Volume81
Issue numberSUPPL. 1
Publication statusPublished - May 1999

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Exercise
Diathermy
Ficus
Cardiac Arrhythmias
Electrocardiography
Heart Rate

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Musialek, P., Kardos, A., Fojt, O., Webb, I., Collin, J., Johnston, J., & Casadei, B. (1999). Right thoracoscopic sympathicotomy increases QT hysteresis during exercise in man. Heart, 81(SUPPL. 1).

Right thoracoscopic sympathicotomy increases QT hysteresis during exercise in man. / Musialek, P.; Kardos, A.; Fojt, O.; Webb, I.; Collin, J.; Johnston, J.; Casadei, B.

In: Heart, Vol. 81, No. SUPPL. 1, 05.1999.

Research output: Contribution to journalArticle

Musialek, P, Kardos, A, Fojt, O, Webb, I, Collin, J, Johnston, J & Casadei, B 1999, 'Right thoracoscopic sympathicotomy increases QT hysteresis during exercise in man', Heart, vol. 81, no. SUPPL. 1.
Musialek P, Kardos A, Fojt O, Webb I, Collin J, Johnston J et al. Right thoracoscopic sympathicotomy increases QT hysteresis during exercise in man. Heart. 1999 May;81(SUPPL. 1).
Musialek, P. ; Kardos, A. ; Fojt, O. ; Webb, I. ; Collin, J. ; Johnston, J. ; Casadei, B. / Right thoracoscopic sympathicotomy increases QT hysteresis during exercise in man. In: Heart. 1999 ; Vol. 81, No. SUPPL. 1.
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AU - Kardos, A.

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AU - Johnston, J.

AU - Casadei, B.

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